Abstract
A critical review of applications of chlorine kinetic isotope effects in studies of organic reactions mechanisms is presented. Reports from the last five years are considered. During this time chlorine kinetic isotope effects were applied mainly in studies of elimination reactions and nucleophilic substitution reactions. In several cases chemical models were also used as models of the intrinsic kinetic isotope effects in several enzymatic reactions. Both experimental and theoretical approaches have been used.
Keywords: chlorine kinetic isotope effects, elimination reactions, triethylamine(tea)-promoted reactions, nucleophilic substitution
Current Organic Chemistry
Title: Chlorine Isotope Effects on Chemical Reactions
Volume: 9 Issue: 1
Author(s): D. Sicinska, M. Rostkowski and P. Paneth
Affiliation:
Keywords: chlorine kinetic isotope effects, elimination reactions, triethylamine(tea)-promoted reactions, nucleophilic substitution
Abstract: A critical review of applications of chlorine kinetic isotope effects in studies of organic reactions mechanisms is presented. Reports from the last five years are considered. During this time chlorine kinetic isotope effects were applied mainly in studies of elimination reactions and nucleophilic substitution reactions. In several cases chemical models were also used as models of the intrinsic kinetic isotope effects in several enzymatic reactions. Both experimental and theoretical approaches have been used.
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Cite this article as:
Sicinska D., Rostkowski M. and Paneth P., Chlorine Isotope Effects on Chemical Reactions, Current Organic Chemistry 2005; 9 (1) . https://dx.doi.org/10.2174/1385272053369295
DOI https://dx.doi.org/10.2174/1385272053369295 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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