Title:Spin Trapping: An Essential Tool for the Study of Diseases Caused by Oxidative Stress
Volume: 15
Issue: 5
Author(s): German Barriga-Gonzalez, Claudio Olea-Azar, Maria C. Zuniga-Lopez, Christian Folch-Cano, Benjamin Aguilera-Venegas, Williams Porcal, Mercedes Gonzalez and Hugo Cerecetto
Affiliation:
Keywords:
DMPO, EPR, ESR, Human diseases, Immuno-spin trapping, Oxidative stress, PBN, Spin traps.
Abstract: Electron spin resonance (ESR), called also electron paramagnetic resonance (EPR) together with the spin trapping
technique, has allowed us to study and understand how free radicals are involved in various pathologies. In this review,
the importance of spin trapping technique in the study of diseases such as cancer, diabetes, hypertension and parasitic
diseases is discussed. In addition, advances in the use of this technique as therapeutic agents and other interesting applications
as the immuno-spin trapping technique are reviewed.
