Title:Rapid and Convenient Synthesis of Triarylpyridine Derivatives using Ammonium Carbamate as an Efficient Solid Ammonia Source Assisted by Microwave Irradiation
Volume: 2
Issue: 2
Author(s): Arash Mouradzadegun, Fatemeh Abadast and Fatemeh Behzadi-Pasham
Affiliation:
Keywords:
Ammonium carbamate, microwave, nucleophilic reaction, pyrylium salts, solid ammonia
source, solvent-free reaction conditions, triarylpyridine.
Abstract: Ammonium carbamate can be used as a very effective reagent for preparation of 2,4,6-
triarylpyridine derivatives from ring transformation of pyrylium salts under solvent-free conditions.
The products are isolated without aqueous work-up in high purity and good yields. The microwave accelerated
the reaction and renders the whole synthesis into a truly eco-friendly protocol.