Title:Markers of Systemic Inflammation in Obstructive Sleep Apnea Syndrome
Volume: 12
Issue: 2
Author(s): Kostas Archontogeorgis, Evangelia Nena, Maria Xanthoudaki and Demosthenes Bouros
Affiliation:
Keywords:
Inflammation, inflammatory markers, obstructive sleep apnea syndrome.
Abstract: Obstructive sleep apnea syndrome (OSAS) is a common disorder characterized by
recurrent episodes of upper airway obstruction resulting in oxygen desaturations and sleep
disruption. OSAS is associated with an augmented risk for cardiovascular and cerebrovascular
morbidity and mortality. Several mechanisms have been proposed to explain the association between
OSAS and cardiovascular dysfunction. Low-grade systemic inflammation may contribute to the
development of the cardiovascular and metabolic diseases associated with OSAS. The purpose of
this review is to summarize current evidence on the association between OSAS and markers of
systemic inflammation.
