摘要
百分之七十五的克罗恩病住院患者遭受营养不良。有三分之一的克罗恩病患者体重指数低于20。百分之六十比例的克罗恩病患者有肌肉无力症状。然而一些炎症性肠病(IBD)患者患有肥胖或者遭受肌肉无力-肥胖。IBD患者多种维生素和营养不足,从而导致高同型半胱氨酸血症等严重的后果,这与一个更高的血栓栓塞性疾病风险相关。IBD患者营养不足是由于摄入不足,吸收不良和蛋白丢失性肠病以及由慢性疾病及其治疗直接诱导的代谢紊乱,尤其是糖皮质激素混乱。在慢性病患者的筛查营养缺陷是必要的。治疗这些缺陷方法包括简单的营养指南、维生素补充剂及最坏情况下的营养治疗。
关键词: 克罗恩病,肠内营养,营养不良,代谢,营养,肥胖症,骨质疏松,肠外营养,肌肉无力,溃疡性结肠炎,维生素。
Current Drug Targets
Title:Nutrition in Adult Patients with Inflammatory Bowel Disease
Volume: 15 Issue: 11
Author(s): Xavier Hebuterne, Jerome Filippi and Stephane M. Schneider
Affiliation:
关键词: 克罗恩病,肠内营养,营养不良,代谢,营养,肥胖症,骨质疏松,肠外营养,肌肉无力,溃疡性结肠炎,维生素。
摘要: Seventy five percent of hospitalized patients with Crohn’s disease suffer from malnutrition. One third of Crohn’s disease patients have a body mass index below 20. Sixty percent of Crohn’s disease patients have sarcopenia. However some inflammatory bowel disease (IBD) patients are obese or suffer from sarcopenic-obesity. IBD patients have many vitamin and nutrient deficiencies, which can lead to important consequences such as hyperhomocysteinemia, which is associated with a higher risk of thromboembolic disease. Nutritional deficiencies in IBD patients are the result of insufficient intake, malabsorption and protein-losing enteropathy as well as metabolic disturbances directly induced by the chronic disease and its treatments, in particular corticosteroids. Screening for nutritional deficiencies in chronic disease patients is warranted. Managing the deficiencies involves simple nutritional guidelines, vitamin supplements, and nutritional support in the worst cases.
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Cite this article as:
Hebuterne Xavier, Filippi Jerome and Schneider M. Stephane, Nutrition in Adult Patients with Inflammatory Bowel Disease, Current Drug Targets 2014; 15 (11) . https://dx.doi.org/10.2174/1389450115666140930150047
DOI https://dx.doi.org/10.2174/1389450115666140930150047 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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