Title:Proteomics in the Search for Biomarkers of Animal Cancer
Volume: 15
Issue: 1
Author(s): Anna Kycko and Michal Reichert
Affiliation:
Keywords:
Cancer biomarker, IHC, proteomics, veterinary oncology.
Abstract: The prevalence of cancer in companion animals has increased in the recent decade, making this disease one of
the major causes of deaths. As in human medicine, veterinary medicine faces the problem of cancer prevention as well as
early diagnosis and effective therapy. Early diagnosis of cancer is crucial for the successful treatment of the disease and
there is a need for biomarkers that could be used as a diagnostic tool, and to guide a targeted therapy or monitor a therapeutic
response. Proteomic technologies that were introduced to human cancer research over a decade ago provide the opportunity
to identify distinct protein patterns for cancer diagnosis and therapy monitoring. These also have potential to be
utilised in veterinary medicine. The present paper summarises the current knowledge about proteomic studies on animal
cancer biomarker research published to date.
