Title:Recent Advances in Cinchona Alkaloid Catalysis for Enantioselective Carbon-Nitrogen Bond Formation Reactions
Volume: 14
Issue: 2
Author(s): Hiroaki Saito and Shinichi Miyairi
Affiliation:
Keywords:
Cinchona alkaloids, enantioselective, N–H bond, organocatalysis, carbene.
Abstract: Organocatalysis and cooperative catalysis are fast growing research areas. In these fields, cinchona alkaloids
and their derivatives play a major role. The ready availability of both pseudo-enantiomeric pairs from natural sources
makes them outstanding catalysts for reactions including oxidation, alkylation, cycloaddition, and carbene insertion. This
short review focuses on recent achievements in the field of asymmetric carbon-nitrogen atom bond formation reactions
using cinchona alkaloids and their derivatives.