Title: Prospects for Combinatorial Chemistry in the Agrosciences
Volume: 8
Issue: 7
Author(s): Stephen D. Lindell and Jurgen Scherkenbeck
Affiliation:
Keywords:
combinatorial library, bioavailability, diversity, virtual screening, target docking, fragment assembly
Abstract: The recent progress and future prospects for the successful application of combinatorial chemistry and high throughput screening within the agrochemical lead discovery process are outlined and discussed. Solid and solution phase library synthesis technologies are reviewed and compared, and the role and importance of bioavailability, diversity and virtual screening in rational library design are detailed.
