![conference banner](/images/conference-banner.jpeg)
Abstract
A series of dihydropyridine analogous was synthesized and evaluated for anticonvulsant activity using PTZ animal model. The main strategies are introducing a non-classical dihydropyridine like structure as anti-seizure agent. Some compounds showed significant anticonvulsant activity in comparison with the control group.
Keywords: Seizure, Anticonvulsant, Hexahydroquinoline derivative, 1, 4-dihydropyrimidine derivative, PTZ animal model, Synthesis.
Letters in Drug Design & Discovery
Title:Synthesis and Anticonvulsant Activity of Some Non-Classical Dihydropyridine Like Structures
Volume: 10 Issue: 9
Author(s): Mohammad Sharifzadeh, Hamid Reza khademi, Ali Almasirad, Zahra rezayan, Mohsen Rezayan Ghayahbashi and Mohsen Amini
Affiliation:
Keywords: Seizure, Anticonvulsant, Hexahydroquinoline derivative, 1, 4-dihydropyrimidine derivative, PTZ animal model, Synthesis.
Abstract: A series of dihydropyridine analogous was synthesized and evaluated for anticonvulsant activity using PTZ animal model. The main strategies are introducing a non-classical dihydropyridine like structure as anti-seizure agent. Some compounds showed significant anticonvulsant activity in comparison with the control group.
Export Options
About this article
Cite this article as:
Sharifzadeh Mohammad, khademi Reza Hamid, Almasirad Ali, rezayan Zahra, Ghayahbashi Rezayan Mohsen and Amini Mohsen, Synthesis and Anticonvulsant Activity of Some Non-Classical Dihydropyridine Like Structures, Letters in Drug Design & Discovery 2013; 10 (9) . https://dx.doi.org/10.2174/15701808113109990015
DOI https://dx.doi.org/10.2174/15701808113109990015 |
Print ISSN 1570-1808 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-628X |
Call for Papers in Thematic Issues
Navigating the Frontier: Probiotics' Promising Path in Combatting Viral Respiratory Infections, Spotlight on Coronaviridae.
Probiotics, well-known for their role in gut health, show promise in preventing and managing respiratory virus infections, particularly in children and at-risk populations. However, the profound influence of novel pathogenic viral RTIs such as coronaviruses has reshaped perspectives on the potential of probiotics. Despite their potential, significant gaps remain in ...read more
![Wayfinder Image](/images/wayfinder.jpg)
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Recent Advances in the Therapeutic Perspectives of Nutlin-3
Current Pharmaceutical Design Quercetin Enhances 5-fluorouracil Sensitivity by Regulating the Autophagic Flux and Inducing Drp-1 Mediated Mitochondrial Fragmentation in Colorectal Cancer Cells
Current Molecular Pharmacology Overactive Bladder - Current Treatment Modalities
Current Women`s Health Reviews Is it Necessary to Calculate Young’s Modulus in AFM Nanoindentation Experiments Regarding Biological Samples?
Micro and Nanosystems Predictors and Clinical Implications of HPV Reservoire Districts for Genital Tract Disease
Current Pharmaceutical Design Cell-free and Cell-based Methods for Characterizing Nuclear Receptor Ligands
Current Medicinal Chemistry - Immunology, Endocrine & Metabolic Agents Step by Step Method Development and Analytical Validation of L929 Bioassay for rTNF-α Potency Evaluation in Manufacturing
Current Pharmaceutical Analysis Biological Denitrification: Screening of Packing Material, Comparison of Denitrification Rate by Pseudomonas aeruginosa and Pseudomonas stutzeri, Application and Design of Bioreactor
Current Environmental Engineering Comprehensive Assessment of ADMET Risks in Drug Discovery
Current Pharmaceutical Design Enhanced Antioxidant and Protective Activities on Retinal Ganglion Cells of Carotenoids-Overexpressing Transgenic Carrot
Current Drug Targets FOXO and FOXM1 in Cancer: The FOXO-FOXM1 Axis Shapes the Outcome of Cancer Chemotherapy
Current Drug Targets Polyunsaturated Fatty Acids in Pathological Retinal Angiogenesis
Current Nutrition & Food Science A Medicinal Chemist’s Perspective Towards Structure Activity Relationship of Heterocycle Based Anticancer Agents
Current Topics in Medicinal Chemistry Tumor Hypoxia as a Modifier of DNA Strand Break and Cross-Link Repair
Current Molecular Medicine Modulatory Effect of Sinapic Acid in Toluene Induced Dementia of Leukoencephalopathy Type in Wistar Rats: a Biochemical Study
The Natural Products Journal The Extent of Hydroxymethylfurfural Formation in Honey by Heating Temperature and Duration
Letters in Organic Chemistry Inflammatory Markers Associated With Diabetes Mellitus – Old and New Players
Current Pharmaceutical Design Determination of three Unsaturated Fatty Acids in Pressure Ulcer Rats Using A UPLC-MS/MS Method
Current Pharmaceutical Analysis Microwave Assisted Synthesis of Pyrazolo[1,5-a]pyrimidine, Triazolo[1,5-a]pyrimidine, Pyrimido[1,2-a]benzimdazole, Triazolo[5,1-c][1,2,4]triazine and Imidazo[2,1-c][1,2,4]triazine
Current Microwave Chemistry Shelf-life of Extra Virgin Olive Oils from Southern Italy
Current Nutrition & Food Science