Title:Pharmacokinetics and Applications of Magnetic Nanoparticles
Volume: 14
Issue: 8
Author(s): Runyi Mao, Jing Wang, Jiao Pei, Songtao Wu, Jie Feng, Yunfeng Lin and Xiaoxiao Cai
Affiliation:
Keywords:
Nanomaterial, magnetic nanoparticles (MNPs), drug delivery system, hyperthermia, cancer, targeting.
Abstract: Nanomaterials possess enormous potential for biomedical applications, while some of the most promising nanomaterials currently
under investigation demonstrate prolonged tissue retention and contain heavy metals. This article investigates the pharmacokinetics
of magnetic nanoparticles (MNPs) to help identify promising candidates with optimal pharmacokinetics and clearance from the body for
biomedical use and synthesize nanomaterials ideal for biomedical use. The term ‘magnetic nanoparticles’ (MNPs) refers to nanoparticles
with ferromagnetism. Such nanoparticles have special characteristics, and many in the field of biological field have undertaken research
involving, e.g., immobilized enzymes and proteins, biological cells, macromolecular separation, drug carriers, and targeted, immune, biological
sensors.