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Abstract
Clinical proteomics studies are extensively being conducted in recent years. We have outlined some views about proteomics progresses for clinical research, via the understanding the molecular mechanisms of carcinogenesis, tumor response to therapy and biomarker identification versus novel therapeutic target-discovery; as well as proteomerelated methods used in cancer research. Integrative concepts of development of novel therapeutic targets and the application of proteomics in drug development are also discussed.
Several aspects are touched including the development of novel therapeutic targets, proteomics as a tool to discover biomarkers, discovery and validation of prognostic and predictive biomarkers, and biobanking versus proteomics.
Finally, we envision the application of clinical proteomics for future personalized cancer therapies can set up a consensus that will be reached amongst the scientific community.
Keywords: Cancer, clinical proteomics, personalized medicine, omics.
Current Proteomics
Title:Clinical Proteomics in Cancer Research
Volume: 10 Issue: 2
Author(s): Elena Lopez, Luis Madero, Gustavo J. Melen, Manuel Ramirez, Dimitrios H. Roukos and William C. Cho
Affiliation:
Keywords: Cancer, clinical proteomics, personalized medicine, omics.
Abstract: Clinical proteomics studies are extensively being conducted in recent years. We have outlined some views about proteomics progresses for clinical research, via the understanding the molecular mechanisms of carcinogenesis, tumor response to therapy and biomarker identification versus novel therapeutic target-discovery; as well as proteomerelated methods used in cancer research. Integrative concepts of development of novel therapeutic targets and the application of proteomics in drug development are also discussed.
Several aspects are touched including the development of novel therapeutic targets, proteomics as a tool to discover biomarkers, discovery and validation of prognostic and predictive biomarkers, and biobanking versus proteomics.
Finally, we envision the application of clinical proteomics for future personalized cancer therapies can set up a consensus that will be reached amongst the scientific community.
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Cite this article as:
Lopez Elena, Madero Luis, Melen J. Gustavo, Ramirez Manuel, Roukos H. Dimitrios and Cho C. William, Clinical Proteomics in Cancer Research, Current Proteomics 2013; 10 (2) . https://dx.doi.org/10.2174/15701646112099990001
DOI https://dx.doi.org/10.2174/15701646112099990001 |
Print ISSN 1570-1646 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6247 |
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The Thematic Issue on "Mass spectrometry data acquisition and analysis for proteomics" aims to explore the latest advancements and challenges in the field of proteomics through the lens of mass spectrometry. Proteomics, the large-scale study of proteins and their functions, plays a crucial role in understanding various biological processes and ...read more
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