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Current Radiopharmaceuticals


ISSN (Print): 1874-4710
ISSN (Online): 1874-4729

Bone Metastases Radiopharmaceuticals: An Overview

Author(s): Vincenzo Cuccurullo, Giuseppe Lucio Cascini, Oscar Tamburrini, Antonio Rotondo and Luigi Mansi

Volume 6, Issue 1, 2013

Page: [41 - 47] Pages: 7

DOI: 10.2174/1874471011306010007

Price: $65


The skeleton is one of the preferential sites for metastases of solid tumors, and metastatic disease is the most common malignancy of the bone. Diagnosis and evaluation of skeletal metastases require more frequently a combined approach of different diagnostic methods. Between the currently available imaging modalities, a major role is devoted to two radionuclide functional techniques namely scintigraphy and positron emission tomography (PET) imaging. Both these techniques require the use of different radiopharmaceuticals. The aim of this paper is to review the most important radiocompounds that can be successfully used to detect and/or characterize bone metastases.

Keywords: Bone metastases, Bone scintigraphy, Tc-99m diphosphonates, F-18 fluoride, F-18 Fluoro-deoxyglucose, Oncotropic radio-agents

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