Title:Applicability and Approaches of (Meth) Acrylate Copolymers (Eudragits) in Novel Drug Delivery Systems
Volume: 7
Issue: 4
Author(s): Kumar Animesh, Moin Afrasim, Rami R. Bommareddy, Ahmed Ayaz, Ravi Shruthi and Hoskote G. Shivakumar
Affiliation:
Keywords:
Applications, polymethacrylates, review
Abstract: This review focuses on the recent developments and future trends dealing with its modifications, encompassing
the different grades of polymethacrylates polymers based formulations. The last three decades of pioneering works
explain it as a new functional material of high potential value in novel drug delivery. Polymethacrylates are synthetic
cationic and anionic copolymers of dimethylaminoethyl methacrylates, methacrylic acid, and methacrylic acid esters in
varying ratios, generating a new and modified patterned polymer due to their electrical characters and pH- dependent
solubility. Based on current research and existing products, some new and futuristic approaches in this fascinating area
have been thoroughly explored and discussed. These polymers are used as release retardant in different formulations like
oral capsules and tablets, film-coating agents for protective purposes and provide sustained release formulations. This
review also screens the current applications of these polymers in the development of microparticles, patches,
nanoparticles, colon targeted formulations, ophthalmic, vaccine delivery, taste masking agent and its pivotal application in
gene delivery systems. This work summarizes the achievements of past which can be extrapolated to characterize the
possible array of polymeric interactions, exploiting their desirable properties for future studies.
