Title:New Insights into HLA-G and Inflammatory Diseases
Volume: 11
Issue: 6
Author(s): Roberta Rizzo, Daria Bortolotti, Olavio R. Baricordi and Enrico Fainardi
Affiliation:
Keywords:
HLA-G, immunity, immune cells, inflammation, pathology, regulation, Human leucocyte antigen-G, anti-inflammatory, HLA-G typing, Allergic disorders
Abstract: Human leucocyte antigen-G (HLA-G) is a non-classical HLA class I molecule with an important role at the
fetus-maternal interface, preventing fetus recognition and abortion. The role of HLA-G as an immune-modulatory and
anti-inflammatory molecule has led to investigate its role in pathological conditions. In these years, HLA-G has been
shown to have an important implication in inflammatory pathologies. The focus of this review is to up-date the scientific
knowledge on the expression of HLA-G molecules in inflammatory conditions.
