Title:Therapeutic Gene Products Delivery by Neuron Stem Cells
Volume: 13
Issue: 12
Author(s): Jie Tan, Yanna Meng, Shiang Huang and Ping Wang
Affiliation:
Keywords:
Stem/progenitor cells, malignant tumors, gene therapy, antibody neural disorder, chemotherapy, metastatic tumors, Breast cancer, Spinal cord injury, stem cell, The nervous system, neural stem cells, fetal tissue, human ntera 2 neurons, gene products
Abstract: Malignant tumors remain virtually untreatable and inevitably lethal despite extensive surgical excision and
adjuvant radio- and chemotherapy. Therefore, the development of more effective tumor-selective therapies is necessary.
Stem/progenitorcells that self-renew, differentiate and display inherent tumor-tropic properties can be exploited for
targeted delivery of therapeutic genes to invasive and metastatic tumors. In this review, we mainly introduce the application
in Glioma, Breast cancer, Spinal cord injury, AD and so on. The promising field of stem cell research as it applies to
regenerative medicine is still in infancy, but its potential appears limitless, and we are blessed to be involved in this exciting
realm of research.
