Title:The Hypothalamic-Neurohypophyseal System: Current and Future Treatment of Vasopressin and Oxytocyn Related Disorders
Volume: 6
Issue: 3
Author(s): Rocco S.Calabro, Domenico Italiano, Danilo Ferrara, Stefania Mondello, Valeria Conti-Nibali, Carlo Salviera and Placido Bramanti
Affiliation:
Keywords:
Hypothalamus, neurohypophysis, oxytocin, pituitary, treatment, vasopressin.
Abstract: The hypothalamus and posterior pituitary form a complex neurohumoral system playing a key role in maintaining
body fluid homeostasis and reproductive function. We review the pathophysiology mechanisms of posterior pituitary
hormones and their implications, beyond water balance and delivery, in social functioning, pair bonding and affiliative
behavior. Actual and future treatments for neurohypophysis related disorders are also discussed, particularly focusing on
the development of new therapeutic compounds and patents.
