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Abstract
A very infrequent report of Listeria monocytogenes meningitis and multiple subtentorial abscesses (cerebellar, bulbar, and pontine in location), occurred in an immunocompetent man, and is described and discussed on the ground of the most recent literature evidences regarding the frequency, presentation, and outcome of this disease. The possibility to resort to combination linezolid therapy in patients who appear to be not responsive to first-line treatment of cerebral abscess of definite origin, and the appearance of anemia as an early untoward event of this novel oxazolidinone antibiotic, are also debated.
Keywords: Listeria monocytogenes, bacterial meningitis, brain abscesses, immunocompetent host, linezolid, diagnosis, cure, untoward events
Current Drug Safety
Title: Linezolid Activity Against Disseminated Listeria monocytogenes Meningitis and Central Nervous System Abscesses: Focus on Early Drug Myelotoxicity
Volume: 2 Issue: 2
Author(s): Roberto Manfredi
Affiliation:
Keywords: Listeria monocytogenes, bacterial meningitis, brain abscesses, immunocompetent host, linezolid, diagnosis, cure, untoward events
Abstract: A very infrequent report of Listeria monocytogenes meningitis and multiple subtentorial abscesses (cerebellar, bulbar, and pontine in location), occurred in an immunocompetent man, and is described and discussed on the ground of the most recent literature evidences regarding the frequency, presentation, and outcome of this disease. The possibility to resort to combination linezolid therapy in patients who appear to be not responsive to first-line treatment of cerebral abscess of definite origin, and the appearance of anemia as an early untoward event of this novel oxazolidinone antibiotic, are also debated.
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Cite this article as:
Manfredi Roberto, Linezolid Activity Against Disseminated Listeria monocytogenes Meningitis and Central Nervous System Abscesses: Focus on Early Drug Myelotoxicity, Current Drug Safety 2007; 2 (2) . https://dx.doi.org/10.2174/157488607780598304
DOI https://dx.doi.org/10.2174/157488607780598304 |
Print ISSN 1574-8863 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3911 |
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