Title: Non Peptidic CCK-2 (Formerly CCK-B) Antagonists: A Five Years Overview
Volume: 2
Issue: 4
Author(s): Anna Maria Capelli, Daniele Donati and Fabrizio Micheli
Affiliation:
Keywords:
cck-2 antagonists, cck-b antagonists, cholecystokinin, neuropeptide, panic,analgesic, schizophrenia,anxiety
Abstract: Cholecystokinin (CCK) receptors are divided into CCK-1 (formerly CCK-A) and CCK-2 (formerly CCK-B) sub-types. CCK is a widely distributed neuropeptide in the brain and is considered a central nervous system transmitter. Possible therapeutic applications for CCK-2 antagonists include panic, anxiety, analgesia, schizophrenia, gastric disorders, and gastrointestinal tumours. This review covers the last five years findings in the field of such molecules