Abstract
The rate of syphilis / HIV co-infection amongst men who have sex with men (MSM) in large urban regions ranges from 20 to 70% [7]. Concurrent HIV infection can alter the clinical presentation of syphilis, the response to treatment, and complicate the diagnosis and clinical course of neurosyphilis [18]. Therefore whether to perform a lumbar puncture (LP) on every co-infected patient in order to diagnose neurosyphilis is controversial. Current clinical guidelines specify the indications for LP, but fall short of recommending LP in certain clinical situations such as early syphilis without neurological involvement. This article reviews the current literature on the relative utility and indications for LP in syphilis / HIV co-infected patients and new research in this area.
Keywords: hiv co-infection, high rapid plasma reagin, cerebrospinal fluid
Current HIV Research
Title: Syphilis and HIV Co-Infection: When is Lumbar Puncture Indicated?
Volume: 3 Issue: 1
Author(s): Derek J. Chan
Affiliation:
Keywords: hiv co-infection, high rapid plasma reagin, cerebrospinal fluid
Abstract: The rate of syphilis / HIV co-infection amongst men who have sex with men (MSM) in large urban regions ranges from 20 to 70% [7]. Concurrent HIV infection can alter the clinical presentation of syphilis, the response to treatment, and complicate the diagnosis and clinical course of neurosyphilis [18]. Therefore whether to perform a lumbar puncture (LP) on every co-infected patient in order to diagnose neurosyphilis is controversial. Current clinical guidelines specify the indications for LP, but fall short of recommending LP in certain clinical situations such as early syphilis without neurological involvement. This article reviews the current literature on the relative utility and indications for LP in syphilis / HIV co-infected patients and new research in this area.
Export Options
About this article
Cite this article as:
Chan J. Derek, Syphilis and HIV Co-Infection: When is Lumbar Puncture Indicated?, Current HIV Research 2005; 3 (1) . https://dx.doi.org/10.2174/1570162052773031
DOI https://dx.doi.org/10.2174/1570162052773031 |
Print ISSN 1570-162X |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4251 |
Call for Papers in Thematic Issues
Management of HIV: Management of HIV: old challenges and new needs
The aim of this thematic issue is to provide the most recent updates regarding the effective management of HIV infection. Antiretroviral therapy (ART) has significantly decreased HIV-related mortality, leading to an enhancement in the quality of life and life expectancy for people living with HIV (PLWH). Despite the numerous advancements ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Delirium in Older Patients – A Review
Current Psychiatry Reviews Seroprevalence of Hepatitis E Virus Infection Among Pregnant Women in Ilam, West of Iran
Infectious Disorders - Drug Targets Conventional (Continuous) EEG Monitoring in the NICU
Current Pediatric Reviews Caenorhabditis elegans-based Model Systems for Antifungal Drug Discovery
Current Pharmaceutical Design Potential Drugs Targeting Microglia: Current Knowledge and Future Prospects
CNS & Neurological Disorders - Drug Targets Diagnosis and Treatment of Pulmonary Fungal Infections in Critically Ill Patients
Current Respiratory Medicine Reviews Clinical Applications of Choline PET/CT in Brain Tumors
Current Pharmaceutical Design Short- and Long-Term Survival of Nonsurgical Intensive Care Patients and its Relation to Diagnosis, Severity of Disease, Age and Comorbidities
Current Aging Science Kynurenine Pathway in Schizophrenia: Pathophysiological and Therapeutic Aspects
Current Pharmaceutical Design Overcoming the Blood-Brain Barrier for Chemotherapy: Limitations, Challenges and Rising Problems
Anti-Cancer Agents in Medicinal Chemistry Arboviral Encephalitis and RNAi Treatment
Central Nervous System Agents in Medicinal Chemistry Editorial [ Hot Topic:Stroke Bugs: Current and Emerging Concepts Relevant to Infection in Cerebrovascular Disease (Guest Editors: Hedley CA Emsley and Angel Chamorro)]
Infectious Disorders - Drug Targets Patent Selections
Recent Patents on Biotechnology COVID-19, the Brain, and the Future: Is Infection by the Novel Coronavirus a Harbinger of Neurodegeneration?
CNS & Neurological Disorders - Drug Targets Community-Acquired Pneumonia in Children
Recent Patents on Inflammation & Allergy Drug Discovery Nanomedicines as Cancer Therapeutics: Current Status
Current Cancer Drug Targets Neuroglial Roots of Neurodegenerative Diseases: Therapeutic Potential of Palmitoylethanolamide in Models of Alzheimer’s Disease
CNS & Neurological Disorders - Drug Targets Response to HAART in Treatment-Naive HIV-Infected Patients with a Prior Diagnosis of Tuberculosis or other Opportunistic Infections
Current HIV Research Pathophysiology of the Vascular Wall and its Relevance for Cerebrovascular Disorders in Aged Rodents
Current Neurovascular Research Microwave Assisted Functionalization of Materials: from the Mesoscale to the Nanoscale
Current Organic Chemistry