Title: Recent Applications of the Simple Hydrocarbon Cyclooctatetrene as a Starting Material for Complex Molecule Synthesis
Volume: 9
Issue: 1
Author(s): Kevin W. Glaeske and William A. Donaldson
Affiliation:
Keywords:
Cyclooctatetraene, oxidation, Cycloaddition, synthesis, complex molecule, epoxide products, pentacycloanammoxic, cyclooctitols, carbonylation reactions, B-Allose
Abstract: Cyclooctatetraene [COT], a simple non-aromatic cyclic polyene, is capable of undergoing a variety of oxidation and cycloaddition reactions to afford polycyclic structures. In addition, complexation of COT or the cycloaddition products with transition metals facilitates bond formation. Recent developments in the reactivity of COT and application to the synthesis of naturally occurring and non-naturally occurring compounds is reviewed.