Abstract
7-benzyl-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-ones were synthesized by base catalytic reactions of nucleophilic reagents (aliphatic amines, alcohols or phenols) with carbodiimides 4, which were obtained from the aza-Wittig reaction of iminophosphoranes 3 with aromatic isocyanates.
Keywords: Aza-Wittig reaction, carbodiimide, iminophosphorane, thieno[2, 3-d]pyrimidin-4(3H)-one, alkyl, antianxiety, antiarrhythmic, antiprotozoal, benzene
Letters in Organic Chemistry
Title: Efficient Synthesis of 7-benzyl-5,6,7,8-tetrahydropyrido[4',3':4',5]thieno [2,3-d]pyrimidin-4(3H)-Ones Via Aza-Wittig Reaction
Volume: 8 Issue: 9
Author(s): Hong Chen, Kai Yan and Ming-Guo Liu
Affiliation:
Keywords: Aza-Wittig reaction, carbodiimide, iminophosphorane, thieno[2, 3-d]pyrimidin-4(3H)-one, alkyl, antianxiety, antiarrhythmic, antiprotozoal, benzene
Abstract: 7-benzyl-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-ones were synthesized by base catalytic reactions of nucleophilic reagents (aliphatic amines, alcohols or phenols) with carbodiimides 4, which were obtained from the aza-Wittig reaction of iminophosphoranes 3 with aromatic isocyanates.
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Cite this article as:
Chen Hong, Yan Kai and Liu Ming-Guo, Efficient Synthesis of 7-benzyl-5,6,7,8-tetrahydropyrido[4',3':4',5]thieno [2,3-d]pyrimidin-4(3H)-Ones Via Aza-Wittig Reaction, Letters in Organic Chemistry 2011; 8 (9) . https://dx.doi.org/10.2174/157017811799304250
DOI https://dx.doi.org/10.2174/157017811799304250 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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