Abstract
An ultrasonic-assisted, one-pot, efficient, convenient procedure for the synthesis of (3-phenylisoxazol-5- yl)methanol derivatives has been developed. (3-Phenylisoxazol-5-yl)-methanol derivatives with biological and pharmaceutical property have been synthesized in moderate to excellent yields. The synthetic methods possess the advantages of high yield, facile operation process and shorter reaction time, and so on.
Keywords: Ultrasound, aldoximes, 1,3-dipolar cycloaddition, nitrile oxide, isoxazole, one-pot synthesis, pharmacophores, hydroxylamine, herbicide, phenylisoxazol
Letters in Organic Chemistry
Title: One-Pot Synthesis of (3-Phenylisoxazol-5-yl)methanol Derivatives Under Ultrasound
Volume: 8 Issue: 4
Author(s): Chuansheng Shen, Yumin Zhang, Yuanming Gan, Tianqi Zhao and Qiang Gu
Affiliation:
Keywords: Ultrasound, aldoximes, 1,3-dipolar cycloaddition, nitrile oxide, isoxazole, one-pot synthesis, pharmacophores, hydroxylamine, herbicide, phenylisoxazol
Abstract: An ultrasonic-assisted, one-pot, efficient, convenient procedure for the synthesis of (3-phenylisoxazol-5- yl)methanol derivatives has been developed. (3-Phenylisoxazol-5-yl)-methanol derivatives with biological and pharmaceutical property have been synthesized in moderate to excellent yields. The synthetic methods possess the advantages of high yield, facile operation process and shorter reaction time, and so on.
Export Options
About this article
Cite this article as:
Shen Chuansheng, Zhang Yumin, Gan Yuanming, Zhao Tianqi and Gu Qiang, One-Pot Synthesis of (3-Phenylisoxazol-5-yl)methanol Derivatives Under Ultrasound, Letters in Organic Chemistry 2011; 8 (4) . https://dx.doi.org/10.2174/157017811795371467
DOI https://dx.doi.org/10.2174/157017811795371467 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
![](/images/wayfinder.jpg)
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Clozapine and Olanzapine but not Risperidone Impair the Pre-Frontal Striatal System in relation to Egocentric Spatial Orientation in a Y-Maze
Current Neurovascular Research Biological and Pharmacological Effects of Gamma-oryzanol: An Updated Review of the Molecular Mechanisms
Current Pharmaceutical Design Dreams and Psychedelics: Neurophenomenological Comparison and Therapeutic Implications
Current Neuropharmacology A Multi-layered Particulate System for Desvenlafaxine Succinate Oral Customized Release
Current Drug Delivery Adverse Drug Reaction Labelling for Atomoxetine, Methylphenidate and Modafinil: Comparison of Product Information for Oral Formulations in Australia, Denmark and the United States
Current Drug Safety Progress on Multi-Modality Molecular Imaging
Current Medical Imaging Psychopathological and Psychosocial Repercussions of Suicide in the Family
Current Psychiatry Research and Reviews Intracranial Cerebrospinal Fluid Volume Evaluation in Healthy People and Hydrocephalus Patients using SPACE Sequence
Current Medical Imaging Memory Enhancing Effect of Black Pepper in the AlCl3 Induced Neurotoxicity Mouse Model is Mediated Through Its Active Component Chavicine
Current Pharmaceutical Biotechnology Haptoglobin Polymorphism and Lacunar Stroke
Current Neurovascular Research A Review of Inadequate and Excessive Weight Gain in Pregnancy
Current Women`s Health Reviews CSF Levels of the Endocannabinoid Anandamide are Reduced in Patients with Untreated Narcolepsy Type 1: A Pilot Study
CNS & Neurological Disorders - Drug Targets DeepInteract: Deep Neural Network Based Protein-Protein Interaction Prediction Tool
Current Bioinformatics Correct Protonation States and Relevant Waters = Better Computational Simulations?
Current Pharmaceutical Design Endothelial Dysfunction and the Effects of TNF Inhibitors on the Endothelium in Psoriasis and Psoriatic Arthritis: A Systematic Review
Current Pharmaceutical Design Targeting Extracellular Matrix Proteolysis for Hemorrhagic Complications of tPA Stroke Therapy
CNS & Neurological Disorders - Drug Targets The Genetics of Problem and Pathological Gambling: A Systematic Review
Current Pharmaceutical Design Combined Biomarkers for Early Alzheimer Disease Diagnosis
Current Medicinal Chemistry Remodeling of Proteostasis Upon Transition to Adulthood is Linked to Reproduction Onset
Current Genomics Contribution of Electrochemistry to the Biomedical and Pharmaceutical Analytical Sciences
Current Drug Delivery