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Mini-Reviews in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-193X
ISSN (Online): 1875-6298

Chemistry and Biological Activities of 1,3-Benzoxathiol-2-ones

Author(s): Walcimar T. Vellasco, Claudia R.B. Gomes and Thatyana R.A. Vasconcelos

Volume 8, Issue 1, 2011

Page: [103 - 109] Pages: 7

DOI: 10.2174/157019311793979882

Price: $65

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Abstract

Benzoxathiolones and its derivatives are important pharmacophores with diversified pharmacological activities like antibacterial, antimycotic, antioxidant and anti-inflammatory. These different biological applications for benzoxathiolone compounds have motivated new studies in searching novel derivatives with better activity results and also other applications in pharmaceutical industry. Owing to the importance of this system, the aim of this review is to present the main aspects of the chemistry and biological properties of 1,3- benzoxathiol-2-ones.

Keywords: 1,3-benzoxathiol-2-ones, synthetic methods, biological activity, 2,6-dihydroxythiophenol, 5,7-dibromo-6-hydroxy-benzoxathiolone, iminobenzoxathiol, Thioaurones, Iminobenzoxathiolones, LYR-71, crystallographic assay, epimerization


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