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Protein & Peptide Letters

Editor-in-Chief

ISSN (Print): 0929-8665
ISSN (Online): 1875-5305

Tityus serrulatus Scorpion Venom and Toxins: An Overview

Author(s): Camila T. Cologna, Silvana Marcussi, Jose R. Giglio, Andreimar M. Soares and Eliane C. Arantes

Volume 16, Issue 8, 2009

Page: [920 - 932] Pages: 13

DOI: 10.2174/092986609788923329

Price: $65

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Abstract

Tityus serrulatus is considered the most dangerous scorpion in South America and responsible for most of the fatal cases. This review will focus on Tityus serrulatus scorpion venom (Tsv), its long-chain Na+-channel toxins (NaTx), which include α- and β-neurotoxins, short-chain K+-channel toxins (KTx), hyaluronidase, proteases and other peptides hitherto identified.

Keywords: Scorpion, Tityus serrulatus venom, neurotoxins, ion channels, hyaluronidase, proteases, peptides


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