Title: Venom-Sweet-Venom: N-Linked Glycosylation in Snake Venom Toxins
Volume: 16
Issue: 8
Author(s): Sandro G. Soares and Leandro L. Oliveira
Affiliation:
Keywords:
N-linked oligosaccharides, snake venom, enzyme activity, serine protease
Abstract: Protein glycosylation represents one of the most important post-translational events, and is a mean of diversifying a protein without recourse to the genome. The venoms produced by snakes contain an abundance of glycoproteins with N-linked carbohydrates. N-linked glycosylation can ensure the correct folding of important functional domains. Characterization of carbohydrates structures aids in development of human therapeutics by snake venom toxins.