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Mini-Reviews in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-193X
ISSN (Online): 1875-6298

The Concept of a Green Drug, Curcumin and It ’ s Derivatives as a Model System

Author(s): K. S. Raja, R. Balambika, S. Dolai and W. Shi

Volume 6, Issue 2, 2009

Page: [152 - 158] Pages: 7

DOI: 10.2174/157019309788167684

Price: $65

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Abstract

Only 5-15% of the ∼25000 existing species of plants have been examined for the presence of biologically active compounds. The ancient medical systems use a much larger palette of herbs for therapy. Systematic drug discovery involving using cues provided from traditional medical systems is bound to produce a new generation of green drugs. Curcumin the primary active ingredient in Curcuma longa is used as a model to enunciate the concept of green drug development. Synthetic and formulation based approaches to optimize the bioactivity of curcumin is presented.

Keywords: Green drug, curcumin, traditional medicine, GRAS, renewable resource, derivative


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