Title: Peptidomimetics and Peptide Backbone Modifications
Volume: 2
Issue: 5
Author(s): Jung-Mo Ahn, Nicholas A. Boyle, Mary T. MacDonald and Kim D. Janda
Affiliation:
Keywords:
peptidomimetics, backbone modifications, hydrophobicity of pseudopeptides, enzymatic stability, amino acids, human, immunodeficiency
Abstract: The replacement of the amide bond in a peptide backbone is a widely used form of peptide mimicry. Several of the most common amide bond surrogates, including peptidomimetic work done in this laboratory, and their biological applications are presented in this review.