Title: Immunotoxins and Other Conjugates: Pre-clinical Studies
Volume: 4
Issue: 5
Author(s): A. Bolognesi and L. Polito
Affiliation:
Keywords:
ribosome-inactivating proteins, toxins, conjugates, immunotoxins, targeting, immunotherapy
Abstract: A wide variety of conjugates containing RIPs, of either chemical or recombinant type, have been made and tested against dangerous cells in vitro and in animal models. Many of these pre-clinical studies will be reviewed here dividing them on the basis of the target cell and the surface molecule specifically recognized.