Abstract
Cyclosporin A (CsA) is a fungal metabolite that has immunomodulatory and anti-inflammatory effects. Cyclosporin binds to cyclophilin, inhibiting CD4-T-cell activation. In this paper we discuss the mechanism of action of CsA and its role as a novel approach for the treatment of allergic disease.
Keywords: allergic contact dermatitis, asthma, atopic dermatitis, cyclosporin, ocular allergic diseases, urticaria
Letters in Drug Design & Discovery
Title: Cyclosporin A: A Therapeutic Strategy in Allergic Diseases
Volume: 1 Issue: 4
Author(s): Nettis Eustachio, Colanardi Maria Cristina and Ferrannini Antonio
Affiliation:
Keywords: allergic contact dermatitis, asthma, atopic dermatitis, cyclosporin, ocular allergic diseases, urticaria
Abstract: Cyclosporin A (CsA) is a fungal metabolite that has immunomodulatory and anti-inflammatory effects. Cyclosporin binds to cyclophilin, inhibiting CD4-T-cell activation. In this paper we discuss the mechanism of action of CsA and its role as a novel approach for the treatment of allergic disease.
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Cite this article as:
Eustachio Nettis, Cristina Maria Colanardi and Antonio Ferrannini, Cyclosporin A: A Therapeutic Strategy in Allergic Diseases, Letters in Drug Design & Discovery 2004; 1 (4) . https://dx.doi.org/10.2174/1570180043398650
DOI https://dx.doi.org/10.2174/1570180043398650 |
Print ISSN 1570-1808 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-628X |
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