Abstract
A series of 7-carbamate derivatives of quercetin were synthesized. Using dichlorodiphenylmethane and benzyl bromide to partly protect the hydroxyl groups, the protected quercetin then reacted with amino acid ester isocyanates, deprotection the hydroxyls with hydrogen using a palladium on carbon catalyst, then treating with ammonia gas to give the ammonium salts of 7-carbamate derivatives of quercetin.
Keywords: Quercetin, 7-carbamate derivatives of quercetin, dichlorodiphenylmethane, isocyanate, ammonium salt
Letters in Organic Chemistry
Title: Syntheses of the Ammonium Salts of 7-Carbamate Derivatives of Quercetin
Volume: 4 Issue: 5
Author(s): Chenglong Wu, Li Cheng, Ying Li, Dong Guo, Shuyan Yu, Xianxue Wu and Yuquan Wei
Affiliation:
Keywords: Quercetin, 7-carbamate derivatives of quercetin, dichlorodiphenylmethane, isocyanate, ammonium salt
Abstract: A series of 7-carbamate derivatives of quercetin were synthesized. Using dichlorodiphenylmethane and benzyl bromide to partly protect the hydroxyl groups, the protected quercetin then reacted with amino acid ester isocyanates, deprotection the hydroxyls with hydrogen using a palladium on carbon catalyst, then treating with ammonia gas to give the ammonium salts of 7-carbamate derivatives of quercetin.
Export Options
About this article
Cite this article as:
Chenglong Wu , Li Cheng , Ying Li , Dong Guo , Shuyan Yu , Xianxue Wu and Yuquan Wei , Syntheses of the Ammonium Salts of 7-Carbamate Derivatives of Quercetin, Letters in Organic Chemistry 2007; 4 (5) . https://dx.doi.org/10.2174/157017807781212021
DOI https://dx.doi.org/10.2174/157017807781212021 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
![Wayfinder Image](/images/wayfinder.jpg)
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
TRPV1 Function in Health and Disease
Current Pharmaceutical Biotechnology NF-κB Blockers Gifted by Mother Nature: Prospectives in Cancer Cell Chemosensitization
Current Pharmaceutical Design Antibody Therapy of Acute and Chronic Leukemias
Current Pharmaceutical Biotechnology New Insights about the Potential Application of the Association of Vitamins C (Sodium Ascorbate) and K3 (Menadione) as Auxiliary Therapy in Cancer Treatment
Medicinal Chemistry Reviews - Online (Discontinued) Gene Expression and Behavior Analysis of PC12 Cells Grown on Synthetic Biodegradable Fibrous Membranes Coated with Natural Biopolymers
Current Nanoscience Withdrawal Notice: Electrophoresis as a Tool for Early Cancer Diagnosis
Anti-Cancer Agents in Medicinal Chemistry Ginkgolic Acids Confer Potential Anticancer Effects by Targeting Pro- Inflammatory and Oncogenic Signaling Molecules
Current Molecular Pharmacology Recent Updates on Oncogenic Signaling of Aurora Kinases in Chemosensitive, Chemoresistant Cancers: Novel Medicinal Chemistry Approaches for Targeting Aurora Kinases
Current Medicinal Chemistry VFP: A Visual Algorithm for Predicting Gene Fusion in RNA-Seq Data
Current Bioinformatics Protein-Protein Interactions and Cancer: Targeting the Central Dogma
Current Topics in Medicinal Chemistry Chemically Functionalized Carbon Nanotubes: Emerging Vectors for Cell Therapy
Mini-Reviews in Medicinal Chemistry The Potential Use of Hormone-Based Therapeutics for the Treatment of Alzheimers Disease
Current Alzheimer Research Editorial [Hot Topic: PET – CT AND RADIOTHERAPY (Guest Editors: Diana Salvo, Annibale Versari & Luigi Mansi)]
Current Radiopharmaceuticals Targeting Tumors Using Estrogen Receptor Ligand Conjugates
Current Cancer Drug Targets Technetium Labeled Small Peptide Radiopharmaceuticals in the Identification of Lung Cancer
Current Pharmaceutical Design Protein Modification by β-N-Acetyl Glucosamine (O-GlcNAc) in Insulin Signaling and Insulin Resistance
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery (Discontinued) In Silico Prediction of P-glycoprotein Binding: Insights from Molecular Docking Studies
Current Medicinal Chemistry Pharmaceutical Measures to Prevent Doxorubicin-Induced Cardiotoxicity
Mini-Reviews in Medicinal Chemistry Unveiling the Role of Nuclear Transport in Epithelial-to-Mesenchymal Transition
Current Cancer Drug Targets Supertargeted Chemistry: Identifying Relationships Between Molecular Structures and their Sub-Cellular Distribution
Current Topics in Medicinal Chemistry