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Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1871-5230
ISSN (Online): 1875-614X

Pro-Inflammatory Cytokines and their Actions on the Metabolic Disturbances Associated with Cancer: Implications in Cachexia

Author(s): Josep M. Argiles, Miriam Toledo, Francisco J. Lopez-Soriano and Silvia Busquets

Volume 10, Issue 4, 2011

Page: [275 - 280] Pages: 6

DOI: 10.2174/187152311797928199

Price: $65

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Abstract

The main aim of the present review is to summarize and evaluate the different molecular mechanisms and catabolic mediators (mainly cytokines) involved in cancer cachexia since they may represent targets for future promising clinical investigations.

Keywords: TNF-, IL-6, IL-1, TWEAK, myostatin, PIF, transcriptional factors, cancer cachexia, anorexia


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