Abstract
Natural products are regarded as vital key source of lead compounds for drug discovery due to their structural diversity and broad array of biological activities. Phenylpropanoid sucrose esters are naturally occurring compounds isolated from various plants and are structurally characterized by a sucrose core connected to one or more Ph-CH=CH-CO- moieties through an ester linkage. These compounds were extensively used in folk medicine and are found to possess many biological activities such as antitumor, antibacterial, antioxidant, antiviral, anti-inflammatory, neuro-protective and glycosidase inhibitory activities. This extensive review, which is the first of its kind on phenylpropanoid sucrose esters, aims to provide an up-to-date account of naturally occurring known phenylpropanoid sucrose esters with special focus on their sources, structures, biological and pharmacological activities.
Keywords: Glycosides, isopropylidene acetal, phenylpropanoid sucrose esters, plant-derived natural product, traditional medicine, drug discovery, biological activities, antibacterial, pharmacological activities
Current Medicinal Chemistry
Title: Phenylpropanoid Sucrose Esters: Plant-Derived Natural Products as Potential Leads for New Therapeutics
Volume: 18 Issue: 21
Author(s): P. Panda, M. Appalashetti and Z. M.A. Judeh
Affiliation:
Keywords: Glycosides, isopropylidene acetal, phenylpropanoid sucrose esters, plant-derived natural product, traditional medicine, drug discovery, biological activities, antibacterial, pharmacological activities
Abstract: Natural products are regarded as vital key source of lead compounds for drug discovery due to their structural diversity and broad array of biological activities. Phenylpropanoid sucrose esters are naturally occurring compounds isolated from various plants and are structurally characterized by a sucrose core connected to one or more Ph-CH=CH-CO- moieties through an ester linkage. These compounds were extensively used in folk medicine and are found to possess many biological activities such as antitumor, antibacterial, antioxidant, antiviral, anti-inflammatory, neuro-protective and glycosidase inhibitory activities. This extensive review, which is the first of its kind on phenylpropanoid sucrose esters, aims to provide an up-to-date account of naturally occurring known phenylpropanoid sucrose esters with special focus on their sources, structures, biological and pharmacological activities.
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Cite this article as:
Panda P., Appalashetti M. and M.A. Judeh Z., Phenylpropanoid Sucrose Esters: Plant-Derived Natural Products as Potential Leads for New Therapeutics, Current Medicinal Chemistry 2011; 18 (21) . https://dx.doi.org/10.2174/092986711796391589
DOI https://dx.doi.org/10.2174/092986711796391589 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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