Title:Recent Advances in the Synthesis and Applications of Partially Protected N-Glycosylamines
Volume: 29
Issue: 5
Author(s): Sheersha Pradhan, Banoth Janhavi and Thangamuthu Mohan Das*
Affiliation:
- Department of Chemistry, School of Basic and Applied Sciences, Central University of Tamil Nadu (CUTN), Thiruvarur 610 005,
India
Keywords:
Glycosides, N-glycosides, C-glycosides, O-glycosides, gelators, organogels, hydrogels, sensor, imines.
Abstract: Due to the compatibility of binding and undergoing chemical modification of
sugar derivatives with a variety of scaffolds, the design of innovative tools for bio-sensing
and bio-marking, energy harvesting, drug design, and delivery is growing steadily. Furthermore,
the chemistry of partially protected sugars has not been explored well in terms of
its applications in smart materials. However, these sugar derivatives possess a unique characteristic
balance between hydrophilic and hydrophobic nature, which makes them act as
gelator molecules. Several synthetic strategies pertaining to synthesis and applications are
known in the literature. The present review mainly focuses on the partially protected monosaccharide-
based N-glycosylamines and their applications, with few examples from Oand
C-glycosides.
