Title:Nanomedicine: An Emerging Tool in Healing Chronic Wounds and its Opportunities
Volume: 2
Author(s): Yukta Kulkarni, Arsh Chanana*, Pooja Gupta, Aditya Narayan, Oma Shanker, Akhilesh Patel, Ujwal Havelikar, Bhabesh Mahato, Dharmendra Singh, Sadia Parveen, Ravindra Pal Singh and Himmat Singh Chawra
Affiliation:
- Department of Pharmaceutics, NIMS Institute of Pharmacy, NIMS University Rajasthan, India
Keywords:
Nanomedicine, Angiogenesis, Chronic wounds, Wounds healing, Nanofibers, Nanotechnology.
Abstract: Chronic wounds generally take a lot of time to recover, which becomes a cause of worry for the patient and also makes it difficult to manage them.
Chronic wound affects the minds of millions of people worldwide, which results in a high mortality rate. Nanomedicine has emerged as a
promising tool in addressing this issue of chronic wounds. Nanomedicine in chronic wound healing holds the potential to revolutionize wound care
by offering various personalized treatments and improving patient outcomes. Advanced wound dressings and nanofibresscaffolds promote tissue
regeneration, which also accelerates wound closure. Nanomedicine is also able to provoke the various cellular and molecular mechanisms that are
involved in the wound microenvironment, showing the anti-inflammatory, antibacterial, and angiogenetic effects. The gene therapy and various
inflammation modulations using this emerging tool of nanotechnology show promising results in managing the various chronic wounds.
Nanomedicine offers innovative approaches to address these challenges. Nanomedicine also plays a crucial role in tissue engineering, which can
also be used for chronic wound treatment. Nanotechnology has enabled the various development of advanced wound dressings and has improved
various properties. Nanomedicine also uses antimicrobial nanomaterials, such as silver nanoparticles, to combat the various infections in chronic
wounds. The main aim of the review is to provide a concise overview of nanomedicine as a recent tool in healing chronic wounds and also its
various opportunities for curing chronic wounds.