Title:Inorganic Nanomaterials for the Light-Driven Antimicrobial Therapy Applications
Volume: 2
Author(s): Noufal Kandoth*Amitava Das*
Affiliation:
- Department of Chemical Sciences, Indian Institute of Science Education and Research (IISER) Kolkata, Mohanpur, 741246, India
- Department of Chemical Sciences, Indian Institute of Science Education and Research (IISER) Kolkata, Mohanpur, 741246, India
Keywords:
Inorganic materials, Transition metals, Photodynamic therapy, ROS, Photoredox changes, Antimicrobial therapy.
Abstract: Bacterial and biofilm infections remain a leading cause of global mortality, prompting a shift beyond conventional antibiotic drug development due
to the rapid emergence of antimicrobial resistance. This mini-review delves into giving a brief understanding of the realm of metal-containing
nanomaterials, emphasizing their potential in antimicrobial phototherapy free from bacterial resistance. The focus extends to transition metalincorporated
materials as a tool to induce photoredox properties akin to photoredox catalysis. Despite highlighting the promise of such materials,
the review also addresses concerns regarding biosafety for their in vivo applications. Nonetheless, the utilization of multifaceted photoredox
strategies leveraging diverse metal oxidation states, alongside the advantageous light-driven physicochemical attributes of nanosystems, show
promise for combatting challenging pathogenic infections using inorganic materials.
