Title:1-Thiosugars: From Synthesis to Applications
Volume: 29
Issue: 5
Author(s): Surabhi Gupta and Charles Gauthier*
Affiliation:
- Unité Mixte de Recherche (UMR) INRS-UQAC, Centre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche
Scientifique (INRS), Chicoutimi, Québec, Canada, G7H 2B1, and Laval, Québec, Canada, H7V 1B7
Keywords:
Thiosugars, thioglycosides, glycoconjugates, carbohydrates, glycodendrimers, metallodrugs, glucosinolates
Abstract: 1-Thiosugars and their glycosides play crucial roles in carbohydrate chemistry,
primarily due to their stability and potential for mimicking O-glycosides. The synthetic
methodologies for thioglycosides pose ongoing challenges. In recent years, researchers have
shown a growing interest in exploring the applications of thiosugars in various fields, including
the development of natural product derivatives, oligo- and polysaccharide mimics,
metallodrugs, and dendrimers. Numerous approaches and protocols have been devised for
the synthesis of thiosugars. This review aims to comprehensively cover the efforts towards
preparing thiosugars and their application as synthetic precursors.
