Abstract
Nitrogen-positioned radicals are chemical entities that have a lengthier history than carbon ones and their high reactivity makes them invaluable. But, despite its power, much of its chemistry is still uncharted. Currently, developed methodologies to access nitrogen-positioned radicals, such as transition metal catalysis or visible-light photoredox methods through a single-electron transfer process, avoiding the use of harmful or toxic reagents, excess raw materials, solvents as well as pre-functionalization steps or extensive synthetic routes are in continuous progress. This revision aims to depict the recent advances in the field of iminyl-radicals’ syntheses, a special class of radicals placed on nitrogen, catalyzed by transition metals or photoredox techniques for the construction of C-N bonds and their synthetic applications. This work serves as a comprehensive guide for the scope of synthetic applications that this kind of radicals could have.
Keywords: Nitrogen-centered radicals, transition metal catalysis, photoredox methods, single-electron transfer process, C-N bonds, iminyl radicals.
Current Organic Chemistry
Title:At the Speed of Light: Recent Advances on Photocatalyzed Generation and Applications of Iminyl Radicals Promoted by Visible-light
Volume: 28 Issue: 18
Author(s): Mario Valle-Sánchez, Osvaldo F. López-Saladino, Nelly González-Rivas, Yoxkin Estévez-Martínez, Bernardo A. Frontana-Uribe and Erick Cuevas-Yañez*
Affiliation:
- Centro Conjunto de Investigación en Química Sustentable UAEM-UNAM, Universidad Autónoma del Estado de México, Carretera Toluca-Atlacomulco Km. 14.5, Toluca, Estado de México, 50200, Mexico
- Facultad de Química, Universidad Autónoma del Estado de México, Paseo Colón Esq. Paseo Tollocan, 50120, Toluca, Mexico
Keywords: Nitrogen-centered radicals, transition metal catalysis, photoredox methods, single-electron transfer process, C-N bonds, iminyl radicals.
Abstract: Nitrogen-positioned radicals are chemical entities that have a lengthier history than carbon ones and their high reactivity makes them invaluable. But, despite its power, much of its chemistry is still uncharted. Currently, developed methodologies to access nitrogen-positioned radicals, such as transition metal catalysis or visible-light photoredox methods through a single-electron transfer process, avoiding the use of harmful or toxic reagents, excess raw materials, solvents as well as pre-functionalization steps or extensive synthetic routes are in continuous progress. This revision aims to depict the recent advances in the field of iminyl-radicals’ syntheses, a special class of radicals placed on nitrogen, catalyzed by transition metals or photoredox techniques for the construction of C-N bonds and their synthetic applications. This work serves as a comprehensive guide for the scope of synthetic applications that this kind of radicals could have.
Export Options
About this article
Cite this article as:
Valle-Sánchez Mario, López-Saladino F. Osvaldo, González-Rivas Nelly, Estévez-Martínez Yoxkin, Frontana-Uribe A. Bernardo and Cuevas-Yañez Erick*, At the Speed of Light: Recent Advances on Photocatalyzed Generation and Applications of Iminyl Radicals Promoted by Visible-light, Current Organic Chemistry 2024; 28 (18) . https://dx.doi.org/10.2174/0113852728301428240517115907
DOI https://dx.doi.org/10.2174/0113852728301428240517115907 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Chemistry and Biology of Carbohydrates
Carbohydrates are one of the most abundant natural products and are considered to be extremely important biomolecules for their ever-increasing impact on chemistry and biology. Their role in several important biological processes, notably energy storage, transport, modulation of protein function, intercellular adhesion, malignant transformation, signal transduction, viral, and bacterial cell ...read more
Electrochemical C-X bond formation
Conventional methods for carrying out carbon–X bond formation are typically conducted at harsh reaction conditions, and rely on expensive catalysts as well as the use of stoichiometric, and perhaps toxic, oxidants. In this regard, electrochemical synthesis has recently been recognized as a sustainable and scalable strategy for the construction of ...read more
From Lab Bench to Algorithm: The Future of Organic Chemistry Powered by AI
Organic chemistry, with its intricate dance of molecules and reactions, is undergoing a transformation fuelled by the power of Artificial Intelligence (AI) and Machine Learning (ML). The integration of AI/ML with Organic Chemistry is revolutionizing the field by enhancing the efficiency and accuracy of chemical research and development. These technologies ...read more
Related Journals
![](/images/wayfinder.jpg)
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements