Title:Nature's Remedy: Exploring Herbal Treatments for Polycystic Ovarian
Syndrome
Volume: 5
Author(s): Meenakshi Attri, Asha Raghav*Hema Chaudhary
Affiliation:
- School of Medical & Allied Sciences, K. R. Mangalam University, Gurugram, 122103, Haryana, India
Keywords:
Polycystic ovarian syndrome, insulin resistance, hyperandrogenism, pathogenesis, herbal medicine, menstrual cycles.
Abstract:
Polycystic Ovarian Syndrome (PCOS) is a complex condition characterized by chronic
ovulation issues and hyperandrogenism, affecting approximately 6% to 20% of women of reproductive
age, depending on diagnostic criteria. Symptoms typically manifest during early adolescence,
presenting as irregular menstrual cycles, anovulation, and acne. While some mechanisms
underlying PCOS development have been identified, its precise etiology and pathophysiology
remain elusive.
This article delves into the pathogenesis and management of PCOS by exploring relevant literature
on PubMed. Various contributing factors to PCOS were meticulously examined, including
epigenetics, environmental toxins, stress, diet, inflammation, oxidative stress, hyperandrogenism,
insulin resistance, and obesity. This review examines the importance of herbal remedies in
addressing Polycystic Ovarian Syndrome (PCOS), focusing on the chemical makeup, mode of
action, and therapeutic uses of specific herbal medications targeting PCOS. However, despite
this investigation, there remains a significant gap in completed clinical trials on repurposed
drugs for PCOS, often with small sample sizes and inconclusive outcomes. Given the limited
research in this area, further studies and carefully planned clinical trials are warranted to understand
PCOS and its management better. Additionally, gaining deeper insights into PCOS could
facilitate the development of novel drugs targeting newly discovered pathways, thereby improving
treatment options for individuals affected by this syndrome.
