Title:Impact of Metabolic Syndrome and Cardiovascular Risk on the Quality of
Life of People Living with HIV
Volume: 22
Issue: 3
Author(s): Ítalo Inácio Pereira, Adrielly Katrine Tozetto Morais Muto, Regyane Ferreira Guimarães Dias, Hélio Ranes de Menezes Filho, Eduardo Vignoto Fernandes, Luiz Fernando Gouvêa-e-Silva*Ludimila Paula Vaz Cardoso
Affiliation:
- Instituto de Biociências, Universidade Federal de Jataí, Jataí, Goiás, Brazil
Keywords:
Acquired immunodeficiency syndrome, HIV, quality of life, metabolic syndrome, dyslipidemias, heart disease risk factors.
Abstract:
Background: The time elapsed since HIV infection diagnosis (TdiagHIV) affects the
quality of life (QoL) and can get worse when chronic illnesses start.
Objective: The aim of this study was to analyze the impact of metabolic syndrome (MetS) and cardiovascular
risk (CVR) on the QoL of people living with HIV (PLHIV).
Methods: Cross-sectional study, with 60 PLHIV followed at a Reference Center in the city of Jataí,
Goiás, Brazil. Data collection involved sociodemographic, clinical, CVR, MetS, and QoL information.
The data were analyzed using descriptive and inferential statistics, with the BioEstat
5.3 program adopting p<0.05.
Results: There was a predominance of men (61.7%), aged ≤38 years (53.3%), with a TdiagHIV of
97.88±85.65 months and use of antiretroviral therapy (ART) of 80.13±69.37 months. The worst
domain of QoL was concern about confidentiality (40 points), and the best was medication concerns
(95 points). MetS predominated at 18.3% and a moderate CVR at 11.7%. MetS was positively
associated with age >38 years, the female sex, with the lowest score in QoL for general function,
and the highest for TdiagHIV and the use of ART (p<0.05). A moderate CRV was positively
related to higher TdiagHIV and ART use, and low HDL-c, and the lowest score for QoL was
found for trust in a professional (p<0.05).
Conclusion: PLHIV who are older, have a higher TdiagHIV, and use ART are more likely to develop
MetS and moderate CVR. The presence of these diseases in PLHIV causes impairment in areas
of QoL.
