Title:Vaccine for Targeted Therapy of Lung Cancer: Advances and
Developments
Volume: 25
Issue: 8
Author(s): Suraj Kumar, Rishabha Malviya*Prerna Uniyal
Affiliation:
- Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, U.P., India
Keywords:
Lung cancer, vaccine, immunotherapy, targeted therapy, cancer, patient care.
Abstract: Considering that lung cancer is a leading global perpetrator, novel treatment approaches
must be investigated. Due to the broad spectrum of lung cancer, conventional therapies including
chemotherapy, radiotherapy, and surgeries, are not always effective and can have adverse
consequences. The present study's overarching objective was to enhance the development of a personalized
vaccine for targeted lung cancer therapy. Vaccination functions by eliciting a strong and
targeted immune response defense by taking advantage of the specific antigens that are expressed
by lung cancer cells. Crucial antigens associated with tumor cells have been identified with the
recognition of the genetic and immunological circumstances of lung cancer in this review. The
vaccine includes these antigens to prime the immune system, directing it toward recognizing and
attacking cancerous cells. In this review, we have addressed the possible benefits of a targeted
vaccine strategy, which include a reduction in off-target effects and an improvement in health outcomes
for patients. These studies highlight the promise of a tailored vaccine in a novel way for the
treatment of lung cancer. The integration of molecular profiling and immunological insights offers
a rationale for the design and implementation of personalized vaccines. While challenges exist,
the promise of improved treatment outcomes and reduced side effects positions targeted vaccine
therapy as a compelling avenue for advancing lung cancer treatment.
