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Review Article

以顺铂为基础的联合治疗增强癌症治疗

卷 25, 期 7, 2024

发表于: 08 April, 2024

页: [473 - 491] 页: 19

弟呕挨: 10.2174/0113894501294182240401060343

价格: $65

Open Access Journals Promotions 2
摘要

顺铂是一种主要的化疗药物，在肿瘤治疗领域具有重要的价值。但其临床疗效受到耐药、复发、预后差、对正常组织有毒性等问题的严重阻碍。以顺铂为基础的联合治疗因其克服耐药性、降低毒性和增强抗癌作用的能力而在临床前和临床癌症研究中受到越来越多的关注。本文综述了三种主要的顺铂类药物联合给药策略及其各自的优缺点。此外，还讨论了涉及顺铂的7种联合疗法，重点介绍了它们的主要治疗效果、临床前研究机制和临床应用。本文还讨论了未来的前景和挑战，旨在为开发以顺铂为基础的最佳联合治疗方案以改善癌症治疗提供指导。

关键词: 顺铂，联合给药策略，联合治疗，改善癌症治疗，化疗药物，肾毒性，肝毒性。

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