Title:Nanoemulgel: An Innovative Carrier for Drug Delivery of Poorly Water-Soluble Drugs
Volume: 15
Issue: 2
Author(s): Prevesh Kumar*, Zaira Hussain, Phool Chandra, Diksha, Varsha Raj, Navneet Verma and Alok Singh
Affiliation:
- Pharmacy Academy, Faculty of Pharmacy, IFTM University, Lodhipur Rajput, Moradabad, India
Keywords:
Nanoemulgel, topical drug delivery, lipophilic drug, absorption enhancer, permeability.
Abstract: Recently, the delivery of hydrophobic/ poorly water-soluble drugs has been a difficult
task. Various approaches have been developed to counter the former and other main issues, such
as solubility, bioavailability, etc. However, only a few formulations have successfully addressed
the problems and nanoemulgels are a standout among them. The nanoemulgel drug delivery approach
combines multiple benefits associated with emulsion and gel technologies to improve active
moiety solubility, bioavailability, and longevity. The article discusses the present status of nanoemulgel
research and development, including its preparation methods and characterization techniques.
Additionally, the possible uses of nanoemulgel in targeted drug delivery and cosmetic/ personal
care products are discussed. Overall, nanoemulgel technology has shown significant
promise as a novel approach to augment the transport of water-insoluble moieties. With further research
as well as development, it is expected to have a substantial impact on the pharmaceutical
and cosmetic industries. This inclusive review highlighted the role of nanoemulgels as a promising
carrier for drug delivery, with an overview of a few illustrations supporting the cause.