Title:Ethnobotanical Use, Phytochemistry and Pharmacological Activities of Clerodendrum colebrookianium (Lamiaceae)
Volume: 21
Issue: 2
Author(s): Aniya Teli, Diptimayee Jena, Lunasmrita Saikia, Nur Shaid Mondal, Saikat Sen, Kirtimaya Mishra and Manish Kumar Gautam*
Affiliation:
- Faculty of Pharmaceutical Science, Assam Down Town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati-781026, Assam, India
Keywords:
Clerodendrum colebrookianium, nutritional food, pharmacological activities, phytochemicals, therapeutic potential, antihypertensive, protein kinase, nutritional food.
Abstract: Clerodendrum colebrookianium (CC) is a small shrub belonging to the genus Clerondendrum
and the family Lamiaceae that is widely distributed in southeast Asian countries like India
and China. The plant generally grows in the wet and arid regions of the globe. It has four angled
branches that bear flowers along with heart-shaped leaves. This review aims to provide vast
knowledge about the pharmacological activities, ethnobotany uses, and the phytochemicals present
in the plant. Additionally, it will advance our understanding of the plant's therapeutic potential
in the years to come. Much available literature regarding the pharmacological properties, ethnobotany
uses, and phytochemistry of C .colebrookianium was collected from a series of scientific
resources including PubMed and Google Scholar. Many Asian countries have a long history of using
plants from the Clerodendrum genus for various medicinal purposes. Different extracts of CC
have demonstrated a wide range of pharmacological effects, including those that are antihypertensive,
hepatoprotective, analgesic, antidiabetic and many more. Phytoconstituents like Steroidsdaucosterol,
beta-sitosterol, colebrin-A, colebrin-B, colebrin-C, colebrin-D, colebrin-D and Glycoside-
clerosterol 3 beta-O-[beta-D-glucoside], Clerosterol (24S/3) (poriferasta-5,25(26)-dien-
3-ol, sitosterol and octacosanol were reported to be present in this plant. This article offers a
summary of the most recent research on the pharmacological, traditional uses and some of the phytochemicals
of C. colebrookianium walp. Even though it offers a wide range of medical benefits,
many of its traditional uses for health have not been well researched. The entire therapeutic potential
of these plants for treating a variety of other disorders could be discovered with the aid of in-
-depth research and studies on the phytoconstituents of the plant and their active principles.