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当代阿耳茨海默病研究

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ISSN (Print): 1567-2050
ISSN (Online): 1875-5828

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Research Article

阿尔茨海默病发病的笔迹标记

卷 20, 期 11, 2023

发表于: 28 February, 2024

页: [791 - 801] 页: 11

弟呕挨: 10.2174/0115672050299338240222051023

价格: $65

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摘要

介绍:阿尔茨海默病对笔迹(AD)有影响。许多研究人员报告了这一事实。因此，检查笔迹特征可能是筛查AD的有效方法。本文的目的是展示AD-HS工具的可靠性和有效性。 方法:现有的大多数研究要么考察写作的语言表现，要么考察某些运动功能。然而，书写是一种复杂的认知和运动活动。由于AD对笔迹的影响是个体的，因此分析完整的笔迹特征是很重要的。AD-HS仪器就是基于这一原理。与对照组相比，AD-HS仪器显示ad诊断患者认知障碍的有效性验证。这项研究是基于对免费手写文本的评估。AD-HS包括40个手写文本和2个手写文本的语言特征。它基于笔迹分析的标准协议。所有特征的累积评估建立了一个定量的AD指标(ADI)，作为可能的AD条件的标记。分析实验包括53名ad诊断者和192个来自现有数据库的手写样本作为对照组。 结果:AD-HS在参与者(平均值为0.49)和对照组(平均值为0.28)的评估ADI上有明显差异。 结论:AD手写标记可作为早期筛查的有效补充工具。当传统的生物标志物和神经学测试无法应用时，它也很有用。AD-HS可以伴随治疗，作为其对人的影响的指示。

关键词: 阿尔茨海默病，认知障碍，精细运动技能，早期筛查，笔迹分析，定量分析。

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