Abstract
Background: Atypical carcinoid (AC) is one of the rarest lung neuroendocrine tumors (NETs) that rarely metastasize to the breast, and only a few cases have been reported in the literature. Positron emission tomography/computed tomography (PET/CT) with somatostatin analogs (SSAs) labeled with Gallium-68 (68Ga) now represents the gold standard for diagnosis and management of NETs. A case of an unusual metastasis to the breast from an AC detected by 68Ga-DOTATATE PET/CT was reported.
Case Presentation: A 73-year-old woman was presented with a right breast lesion found on mammography screening, which revealed a metastatic neuroendocrine tumor by histopathological analysis with a tru-cut biopsy. Subsequently, 68Ga-DOTATATE PET/CT imaging performed for the initial evaluation showed increased radiotracer uptake in the lesion in the right breast as well as the nodular lesion in the middle lobe of the right lung, which was histologically confirmed to be AC.
Conclusion: Metastasis of uncommon AC of the lung to the breast is extremely rare. However, it is essential to properly differentiate metastatic tumors from primary disease due to differences in clinical management and prognosis, and 68Ga-DOTATATE PET/CT is a unique diagnostic tool with the advantage of whole-body imaging.
Keywords: Neuroendocrine tumor, Lung, Carcinoid, Breast metastasis, PET/CT, 68Ga-DOTATATE.
Call for Papers in Thematic Issues
Emerging Trends & Techniques in Medical Imaging using Machine Learning and Deep Learning Techniques
This special issue will aim to discuss different approaches, initiatives and applications in Medical Imaging fields (including Machine Intelligence, Mining Engineering, Modeling and Simulation, Computer, Communication, Networking and Information Engineering, Systems Engineering, Innovative Computing Systems, Adaptive Technologies for Sustainable Growth, and Theoretical and Applied Sciences). This collection should inspire various ...read more
Intelligent Information Retrieval for Multispectral and Hyperspectral Imaging
Multispectral and hyperspectral imaging is an interdisciplinary research area, widely focuses on spectral, spatial, and temporal data. It offers a plethora of opportunities to efficiently analyze the vast area of the earth's surface. However, there are numerous factors such as dimensionality and size of the hyperspectral data, lesser training samples, ...read more
Multimodal Imaging Using Spectroscopic Techniques for Improved Surgical Guidance
The majority of patients with solid malignancies have surgical excision as their primary and most successful method of medical care. On the other hand, patients experience recurrence and subsequent recurrence. Their objective was to provide a simpler and more concise explanation of the obstacles faced by physicians and the ways ...read more
Quantum Machine Learning for Medical Data and Imaging
Quantum computing has promised a significant speedup in certain computationally intensive tasks that are intractable on classical computers. Researchers in quantum machine learning, such as those working in computer vision, image processing, biomedical analysis, and related topics, may play an important role in comprehending and working on complicated medical data, ...read more
12