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Current Drug Delivery

Editor-in-Chief

ISSN (Print): 1567-2018
ISSN (Online): 1875-5704

Review Article

Current Progress and Emerging Role of Essential Oils in Drug Delivery Therapeutics

In Press, (this is not the final "Version of Record"). Available online 22 February, 2024
Author(s): Rokeya Sultana, Sourav Mohanto, Adrija Bhunia, Aritra Biswas, Mohammad Shabib Akhtar, Vijay Mishra, Dimple Modi, Alaa Aa Aljabali, Murtaza Tambuwala* and Md. Faiyazuddin*
Published on: 22 February, 2024

DOI: 10.2174/0115672018287719240214075810

Price: $95

Abstract

The utilization of novel drug delivery systems loaded with essential oils has gained significant attention as a promising approach for biomedical applications in recent years. Plants possess essential oils that exhibit various medicinal properties, i.e., anti-oxidant, anti-microbial, anti- inflammatory, anti-cancer, immunomodulatory, etc., due to the presence of various phytoconstituents, including terpenes, phenols, aldehydes, ketones, alcohols, and esters. An understanding of conventional and advanced extraction techniques of Essential Oils (EOs) from several plant sources is further required before considering or loading EOs into drug delivery systems. Therefore, this article summarizes the various extraction techniques of EOs and their existing limitations. The in-built biological applications of EOs are of prerequisite importance for treating several diseases. Thus, the mechanisms of action of EOs for anti-inflammatory, anti-oxidant, anti-bacterial activities, etc., have been further explored in this article. The encapsulation of essential oils in micro or nanometric systems is an intriguing technique to render adequate stability to the thermosensitive compounds and shield them against environmental factors that might cause chemical degradation. Thus, the article further summarizes the advanced drug delivery approaches loaded with EOs and current challenges in the future outlook of EOs for biomedical applications.

Keywords: Essential oil, extraction, drug delivery system, inflammation, anti-oxidant, anti-cancer.


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