Abstract
The utilization of novel drug delivery systems loaded with essential oils has gained significant attention as a promising approach for biomedical applications in recent years. Plants possess essential oils that exhibit various medicinal properties, i.e., anti-oxidant, anti-microbial, anti- inflammatory, anti-cancer, immunomodulatory, etc., due to the presence of various phytoconstituents, including terpenes, phenols, aldehydes, ketones, alcohols, and esters. An understanding of conventional and advanced extraction techniques of Essential Oils (EOs) from several plant sources is further required before considering or loading EOs into drug delivery systems. Therefore, this article summarizes the various extraction techniques of EOs and their existing limitations. The in-built biological applications of EOs are of prerequisite importance for treating several diseases. Thus, the mechanisms of action of EOs for anti-inflammatory, anti-oxidant, anti-bacterial activities, etc., have been further explored in this article. The encapsulation of essential oils in micro or nanometric systems is an intriguing technique to render adequate stability to the thermosensitive compounds and shield them against environmental factors that might cause chemical degradation. Thus, the article further summarizes the advanced drug delivery approaches loaded with EOs and current challenges in the future outlook of EOs for biomedical applications.
Keywords: Essential oil, extraction, drug delivery system, inflammation, anti-oxidant, anti-cancer.
Current Drug Delivery
Title:Current Progress and Emerging Role of Essential Oils in Drug Delivery Therapeutics
Volume: 21
Author(s): Rokeya Sultana, Sourav Mohanto, Adrija Bhunia, Aritra Biswas, Mohammad Shabib Akhtar, Vijay Mishra, Dimple Modi, Alaa Aa Aljabali, Murtaza Tambuwala*Md. Faiyazuddin*
Affiliation:
- Lincoln Medical School - Universities of Nottingham and Lincoln, University of Lincoln, Brayford Pool, Lincoln, LN6 7TS, Lincolnshire, UK
- School of Pharmacy, Al-Karim University, Katihar 854106, Bihar, India
Keywords: Essential oil, extraction, drug delivery system, inflammation, anti-oxidant, anti-cancer.
Abstract: The utilization of novel drug delivery systems loaded with essential oils has gained significant attention as a promising approach for biomedical applications in recent years. Plants possess essential oils that exhibit various medicinal properties, i.e., anti-oxidant, anti-microbial, anti- inflammatory, anti-cancer, immunomodulatory, etc., due to the presence of various phytoconstituents, including terpenes, phenols, aldehydes, ketones, alcohols, and esters. An understanding of conventional and advanced extraction techniques of Essential Oils (EOs) from several plant sources is further required before considering or loading EOs into drug delivery systems. Therefore, this article summarizes the various extraction techniques of EOs and their existing limitations. The in-built biological applications of EOs are of prerequisite importance for treating several diseases. Thus, the mechanisms of action of EOs for anti-inflammatory, anti-oxidant, anti-bacterial activities, etc., have been further explored in this article. The encapsulation of essential oils in micro or nanometric systems is an intriguing technique to render adequate stability to the thermosensitive compounds and shield them against environmental factors that might cause chemical degradation. Thus, the article further summarizes the advanced drug delivery approaches loaded with EOs and current challenges in the future outlook of EOs for biomedical applications.
Export Options
About this article
Cite this article as:
Sultana Rokeya, Mohanto Sourav, Bhunia Adrija, Biswas Aritra, Akhtar Mohammad Shabib, Mishra Vijay, Modi Dimple, Aljabali Aa Alaa, Tambuwala Murtaza*, Faiyazuddin Md.*, Current Progress and Emerging Role of Essential Oils in Drug Delivery Therapeutics, Current Drug Delivery 2024; 21 () . https://dx.doi.org/10.2174/0115672018287719240214075810
DOI https://dx.doi.org/10.2174/0115672018287719240214075810 |
Print ISSN 1567-2018 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5704 |
Call for Papers in Thematic Issues
Advancements in Robotic and AI-based Drug Discovery and Delivery for Neurological Disorders
Neurological disorders, including Alzheimer's disease, Parkinson's disease, epilepsy, and brain tumors, pose significant challenges in drug delivery due to the blood-brain barrier's intricate structure and the complexity of neuronal networks. Traditional drug delivery methods often fall short in reaching therapeutic concentrations within the central nervous system, limiting treatment efficacy and ...read more
Electrospun Fibers as Drug Delivery Systems
In recent years, electrospun fibers have attracted considerable attention as potential platforms for drug delivery due to their distinctive properties and adaptability. These fibers feature a notable surface area-to-volume ratio and can be intentionally designed with high porosity, facilitating an increased capacity for drug loading and rendering them suitable for ...read more
Nanoemulsions in cancer therapy
Solid tumors are characterized by leaky vascular structure, defective angiogenesis and high interstitial fluid load, providing opportunities for nanoparticles to preferentially exudate and be retained in tumors. This phenomenon is commonly referred to as the enhanced permeability and retention (EPR) effect, which is considered to be an important reason why ...read more
Pioneering Drug Delivery Strategies for Enhanced Cancer Immunotherapies
The landscape of cancer treatment has been fundamentally transformed by the advent of immunotherapy, a modality that harnesses the body's immune system to recognize and combat malignant cells. Despite its remarkable successes, the full potential of cancer immunotherapy is yet to be realized, largely due to limitations in targeted delivery, ...read more
![](/images/wayfinder.jpg)
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Vitamin D Analogs- Drug Design Based on Proteins Involved in Vitamin D Signal Transduction
Current Drug Targets - Immune, Endocrine & Metabolic Disorders Nitric Oxide: State of the Art in Drug Design
Current Medicinal Chemistry Integrated Analysis of mRNA-seq and miRNA-seq to Identify c-MYC, YAP1 and miR-3960 as Major Players in the Anticancer Effects of Caffeic Acid Phenethyl Ester in Human Small Cell Lung Cancer Cell Line
Current Gene Therapy Cytotoxic and Allergenic Potential of Bioactive Proteins and Peptides
Current Pharmaceutical Design A Comprehensive Review on Hydrogels
Current Drug Delivery Catalytic Features, Regulation and Function of Myocardial Phospholipase A2
Current Medicinal Chemistry - Cardiovascular & Hematological Agents Peptide Self-assembly: From Toxins to Amyloid Fibrils and Nanotubes
Current Topics in Medicinal Chemistry Resveratrol and Neurodegenerative Diseases: Activation of SIRT1 as the Potential Pathway towards Neuroprotection
Current Neurovascular Research Targeting Signaling Pathway by Curcumin in Osteosarcoma
Current Molecular Pharmacology Unsupervised Imbalanced Registration for Enhancing Accuracy and Stability in Medical Image Registration
Current Medical Imaging Crystal Structure of the Pseudomonas aeruginosa MurG: UDP-GlcNAc Substrate Complex
Protein & Peptide Letters Green Synthesis of Silver Nanoparticle using Sechium edule Aqueous Extract and Study of Antimicrobial and Catalytic Activity
Current Nanomaterials Isolation of Achyrobichalcone from Achyrocline satureioides by High- Speed Countercurrent Chromatography
Current Pharmaceutical Biotechnology Impedance based Microfluidic Biosensor for Cell Study
Micro and Nanosystems One-pot Synthesis of Dihydropyrano[2,3-c]chromenes via a Three-component Reaction in Aqueous Media
Combinatorial Chemistry & High Throughput Screening Impact of Liver Cancer Somatic Mutations on Protein Structures and Functions
Current Proteomics QSAR Models for Proteins of Parasitic Organisms, Plants and Human Guests: Theory, Applications, Legal Protection, Taxes, and Regulatory Issues
Current Proteomics Electrochemical DNA Sensors: From Nanoconstruction to Biosensing
Current Organic Chemistry Emerging Vascular Risk Factors in Women: Any Differences from Men?
Current Medicinal Chemistry High-throughput Genotyping Methods for Pharmacogenomic Studies
Current Pharmacogenomics