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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

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Editorial

Targeting Cysteine and Serine Proteases to Discover New Drugs Against Neglected Tropical Diseases

Author(s): Igor José dos Santos Nascimento and Ricardo Olimpio de Moura

Volume 31, Issue 16, 2024

Published on: 14 February, 2024

Page: [2133 - 2134] Pages: 2

DOI: 10.2174/092986733116240214143511

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[1]
Nascimento, I.J. dos S.; Cavalcanti, M. de A.T.; de Moura, R.O. Exploring N-myristoyltransferase as a promising drug target against parasitic neglected tropical diseases. Eur. J. Med. Chem., 2023, 258, 115550.
[2]
De Souza, M.; Medeiros, D.C.; de Moura, R.O.; dos Santos Nascimento, I.J. Pharmacokinetic limitations to overcome and enable K777 as a potential drug against chagas disease. Curr. Pharm. Des., 2023, 29, 2359-2360.
[3]
dos Santos Nascimento, I.J.; de Aquino, T.M.; da Silva-Júnior, E.F. Cruzain and rhodesain inhibitors: last decade of advances in seeking for new compounds against American and African trypanosomiases. Curr. Top. Med. Chem., 2021, 21, 1871-1899.
[4]
dos Santos Nascimento, I.J.; da Silva Rodrigues, É.E.; da Silva, M.F.; de Araújo-Júnior, J.X.; de Moura, R.O. Advances in computational methods to discover new NS2B-NS3 inhibitors useful against dengue and zika viruses. Curr. Top. Med. Chem., 2022, 22, 2435-2462.
[5]
Saha, A. Pushpa; Moitra, S.; Basak, D.; Brahma, S.; Mondal, D.; Molla, S.H.; Samadder, A.; Nandi, S. Targeting cysteine proteases and their inhibitors to combat trypanosomiasis. Curr. Med. Chem., 2024, 31(16), 2135-2169.
[6]
Giroud, M.; Kuhn, B.; Haap, W. Drug discovery efforts to identify novel treatments for neglected tropical diseases - cysteine protease inhibitors. Curr. Med. Chem., 2024, 31(16), 2170-2194.
[7]
Akram, M.; Hameed, S.; Hassan, A.; Khan, K. Development in the inhibition of dengue proteases as drug targets. Curr. Med. Chem., 2024, 31(16), 2195-2233.
[8]
Hernández González, J.E.; Salas-Sarduy, E.; Alvarez, L.H.; Valiente, P.A.; Arni, R.K.; Pascutti, P.G. Three decades targeting falcipains to develop antiplasmodial agents: What have we learned and what can be done next? Curr. Med. Chem., 2024, 31(16), 2234-2263.
[9]
Nascimento, I.; Albino, S.; Menezes, K.; Cavalcanti, M.; Oliveira, M.; Mali, S.; Moura, R. Targeting SmCB1: Perspectives and insights to design antischistosomal drugs. Curr. Med. Chem., 2024, 31(16), 2264-2284.
[10]
Prates, J.L.B.; Lopes, J.R.; Chin, C.M.; Ferreira, E.I.; dos Santos, J.L.; Scarim, C.B. Discovery of novel inhibitors of cruzain cysteine protease of Trypanosoma cruz. Curr. Med. Chem., 2024, 31(16), 2285-2308.

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