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Abstract
The potential of nanotechnology in advancing the diagnosis and treatment of neurodegenerative diseases is explored in this comprehensive literature review. The findings of these studies suggest that nanotechnology has the capacity to improve existing therapeutic approaches, create novel and safe compounds, and develop more precise imaging techniques and diagnostic methods for neurodegenerative diseases. With the emergence of the nanomedicine era, a new and innovative approach of diagnosing and treating these conditions has been introduced. Notably, the researchers' development of a nanocarrier drug delivery tool demonstrates immense potential compared to conventional therapy, as it maximizes therapeutic efficacy and minimizes undesirable as side effects.
Keywords: Nanocarriers, neurodegenerative diseases, drug delivery, nanomedicine, diagnostics, blood-brain barrier.
[http://dx.doi.org/10.1016/j.arabjc.2017.05.011]
[http://dx.doi.org/10.3892/br.2021.1418] [PMID: 33728048]
[http://dx.doi.org/10.1186/s12951-018-0392-8] [PMID: 30231877]
[http://dx.doi.org/10.3390/polym15071596] [PMID: 37050210]
[http://dx.doi.org/10.2147/IJN.S121956] [PMID: 28243086]
[http://dx.doi.org/10.1016/j.eurpolymj.2023.112111]
[http://dx.doi.org/10.1016/j.jddst.2023.105040]
[http://dx.doi.org/10.1186/s12943-022-01708-4] [PMID: 36635761]
[http://dx.doi.org/10.1208/s12249-023-02670-0] [PMID: 37973643]
[http://dx.doi.org/10.1016/j.drudis.2023.103819] [PMID: 37940034]
[http://dx.doi.org/10.1002/adfm.202307074]
[http://dx.doi.org/10.1016/j.envres.2023.116894] [PMID: 37586450]
[http://dx.doi.org/10.1016/j.ijpharm.2023.123276] [PMID: 37516217]
[http://dx.doi.org/10.3390/pharmaceutics14081576] [PMID: 36015202]
[http://dx.doi.org/10.1080/09205063.2022.2065408] [PMID: 35404217]
[http://dx.doi.org/10.1186/s43094-021-00331-2]
[http://dx.doi.org/10.1016/j.molliq.2023.123037]
[http://dx.doi.org/10.1016/j.ijbiomac.2023.127143] [PMID: 37793512]
[http://dx.doi.org/10.3390/molecules25010112] [PMID: 31892180]
[http://dx.doi.org/10.1155/2014/291013]
[http://dx.doi.org/10.4103/2231-4040.82950] [PMID: 22171298]
[http://dx.doi.org/10.3390/nano12183226] [PMID: 36145012]
[http://dx.doi.org/10.3390/pr8080947]
[http://dx.doi.org/10.1016/j.chphi.2023.100355]
[http://dx.doi.org/10.1016/j.rechem.2022.100633]
[http://dx.doi.org/10.1016/j.molstruc.2023.135148]
[http://dx.doi.org/10.4161/biom.24717] [PMID: 23628868]
[http://dx.doi.org/10.1073/pnas.1516247112] [PMID: 26598696]
[PMID: 26236139]
[http://dx.doi.org/10.1186/s13024-019-0333-5] [PMID: 31375134]
[http://dx.doi.org/10.1038/s41573-020-0090-8] [PMID: 33277608]
[http://dx.doi.org/10.3390/ijms222111654] [PMID: 34769082]
[http://dx.doi.org/10.1016/j.colsurfb.2022.112999] [PMID: 36368148]
[http://dx.doi.org/10.7150/thno.21254] [PMID: 29556336]
[http://dx.doi.org/10.3390/polym15092196] [PMID: 37177342]
[http://dx.doi.org/10.1016/j.addr.2018.10.011] [PMID: 30421721]
[http://dx.doi.org/10.1038/natrevmats.2017.14] [PMID: 29876137]
[http://dx.doi.org/10.1007/s10311-021-01342-4] [PMID: 34803553]
[http://dx.doi.org/10.1021/acs.nanolett.3c03222] [PMID: 37991895]
[http://dx.doi.org/10.1126/scitranslmed.adi1617] [PMID: 37910601]
[http://dx.doi.org/10.1038/s41551-022-00965-4] [PMID: 36456857]
[http://dx.doi.org/10.1016/j.biomaterials.2022.121690] [PMID: 35965114]
[http://dx.doi.org/10.1155/2021/5550938] [PMID: 34285915]
[http://dx.doi.org/10.3390/biomedicines11061752] [PMID: 37371847]
[http://dx.doi.org/10.3389/fbioe.2022.1042986] [PMID: 36466349]
[http://dx.doi.org/10.1016/j.bbagen.2024.130559]
[http://dx.doi.org/10.2478/jtim-2021-0054] [PMID: 36860633]
[http://dx.doi.org/10.1016/j.ncl.2017.01.005] [PMID: 28410659]
[http://dx.doi.org/10.1146/annurev-cellbio-040320-120625] [PMID: 33021824]
[http://dx.doi.org/10.1038/s41380-021-01249-0] [PMID: 34456336]
[http://dx.doi.org/10.1007/s12017-009-8104-z] [PMID: 20232515]
[http://dx.doi.org/10.3233/JAD-2010-1221] [PMID: 20061647]
[http://dx.doi.org/10.1523/JNEUROSCI.23-01-00029.2003] [PMID: 12514198]
[http://dx.doi.org/10.1016/j.biomaterials.2010.04.044] [PMID: 20553982]
[http://dx.doi.org/10.3389/fnagi.2022.879114] [PMID: 35875806]
[http://dx.doi.org/10.1016/j.nano.2011.05.009] [PMID: 21703989]
[http://dx.doi.org/10.1016/j.biomaterials.2011.04.020] [PMID: 21529932]
[http://dx.doi.org/10.1166/jnn.2007.330] [PMID: 17450915]
[http://dx.doi.org/10.1016/S0079-6123(08)80005-2] [PMID: 20302830]
[http://dx.doi.org/10.1016/j.neulet.2009.03.064] [PMID: 19429118]
[http://dx.doi.org/10.1039/c3dt50406a] [PMID: 23487286]
[http://dx.doi.org/10.1111/j.1471-4159.2005.03340.x] [PMID: 16181413]
[http://dx.doi.org/10.1016/j.neulet.2006.07.020] [PMID: 16919875]
[http://dx.doi.org/10.1021/acs.jmedchem.0c01480] [PMID: 33023291]
[http://dx.doi.org/10.1155/2020/3534570] [PMID: 33123310]
[http://dx.doi.org/10.2147/IJN.S305851] [PMID: 34234432]
[http://dx.doi.org/10.3390/ph11040109] [PMID: 30347635]
[http://dx.doi.org/10.1016/j.ejpb.2008.03.009] [PMID: 18472255]
[http://dx.doi.org/10.1016/0140-6736(91)92978-B] [PMID: 1674295]
[http://dx.doi.org/10.2174/1871527315666160202124518] [PMID: 26831262]
[http://dx.doi.org/10.1073/pnas.0409336102] [PMID: 15695586]
[http://dx.doi.org/10.1016/j.ijleo.2019.163039]
[http://dx.doi.org/10.1016/j.saa.2020.118174] [PMID: 32106034]
[http://dx.doi.org/10.1016/j.jece.2021.105513]
[http://dx.doi.org/10.1016/j.talanta.2011.12.002] [PMID: 22284471]
[http://dx.doi.org/10.1016/j.sab.2016.04.009]
[http://dx.doi.org/10.1016/j.ab.2008.11.043] [PMID: 19111516]
[http://dx.doi.org/10.1007/s00604-017-2122-6]
[PMID: 20871152]
[http://dx.doi.org/10.1016/j.neuroimage.2011.01.023] [PMID: 21255656]
[PMID: 20721294]
[http://dx.doi.org/10.1097/YCO.0000000000000310] [PMID: 28009724]
[http://dx.doi.org/10.2174/1389200219666180305144143] [PMID: 29512448]
[http://dx.doi.org/10.1385/JMN:24:1:055] [PMID: 15314250]
[http://dx.doi.org/10.1016/j.brainres.2004.08.004] [PMID: 15464749]
[http://dx.doi.org/10.1021/acsmedchemlett.9b00456] [PMID: 32071677]
[http://dx.doi.org/10.1021/acs.molpharmaceut.7b01070]
[http://dx.doi.org/10.1016/j.bmc.2020.115884] [PMID: 33338795]
[http://dx.doi.org/10.1117/1.JNP.15.026010]
[http://dx.doi.org/10.2174/1568026616666161222121229] [PMID: 28017151]
[http://dx.doi.org/10.1186/s13024-019-0306-8] [PMID: 30665447]
[http://dx.doi.org/10.3390/ijms241512116] [PMID: 37569491]
[http://dx.doi.org/10.3390/cells12182283] [PMID: 37759503]
[http://dx.doi.org/10.3390/brainsci12020148] [PMID: 35203912]
[http://dx.doi.org/10.1097/WCO.0000000000001173] [PMID: 37387459]
[http://dx.doi.org/10.1016/j.jddst.2021.102793]
[http://dx.doi.org/10.1021/acsomega.3c04862] [PMID: 38024675]
[http://dx.doi.org/10.3389/fbioe.2021.672594] [PMID: 34113606]
[http://dx.doi.org/10.1016/j.jconrel.2023.06.026] [PMID: 37343725]
[http://dx.doi.org/10.1021/acsanm.3c02749]
[http://dx.doi.org/10.3390/ma16020699] [PMID: 36676436]
[http://dx.doi.org/10.1515/ntrev-2023-0158]
[http://dx.doi.org/10.4252/wjsc.v15.i7.687] [PMID: 37545757]
[http://dx.doi.org/10.1001/archneur.64.1.137] [PMID: 17210824]
[http://dx.doi.org/10.4103/aian.AIAN_169_18] [PMID: 30532351]
[http://dx.doi.org/10.1001/jama.2014.3654] [PMID: 24756517]
[http://dx.doi.org/10.1016/j.ijpharm.2011.07.036] [PMID: 21821107]
[http://dx.doi.org/10.1056/NEJMct0800326] [PMID: 19052127]
[http://dx.doi.org/10.1016/j.ijbiomac.2017.12.056] [PMID: 29247729]
[http://dx.doi.org/10.1016/j.jns.2009.09.032] [PMID: 19909981]
[http://dx.doi.org/10.1002/mds.20276] [PMID: 15390035]
[http://dx.doi.org/10.1212/01.WNL.0000149637.70961.4C] [PMID: 15668416]
[http://dx.doi.org/10.1002/jgm.1152] [PMID: 18085726]
[http://dx.doi.org/10.1016/j.jconrel.2011.02.022] [PMID: 21362449]
[http://dx.doi.org/10.1602/neurorx.2.1.108] [PMID: 15717062]
[http://dx.doi.org/10.1126/science.1120027] [PMID: 16543451]
[http://dx.doi.org/10.1016/j.parkreldis.2007.11.012] [PMID: 18329315]
[PMID: 22619544]
[http://dx.doi.org/10.3109/1061186X.2015.1020809] [PMID: 25758751]
[http://dx.doi.org/10.1016/0014-4886(92)90053-S] [PMID: 1735466]
[http://dx.doi.org/10.1016/j.ijpharm.2009.08.021] [PMID: 19703530]
[http://dx.doi.org/10.1002/jbm.a.35312] [PMID: 25131611]
[http://dx.doi.org/10.3109/03639045.2013.789051] [PMID: 23600649]
[http://dx.doi.org/10.1007/s00216-006-0314-8] [PMID: 16568294]
[http://dx.doi.org/10.1002/chem.201001654] [PMID: 21038326]
[http://dx.doi.org/10.1021/nn900813b] [PMID: 19691350]
[http://dx.doi.org/10.1007/s11481-008-9115-5] [PMID: 18633713]
[http://dx.doi.org/10.1007/s00216-010-4273-8] [PMID: 20953867]
[http://dx.doi.org/10.1021/ac048691v] [PMID: 15762558]