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Central Nervous System Agents in Medicinal Chemistry

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ISSN (Print): 1871-5249
ISSN (Online): 1875-6166

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Mini-Review Article

Network Reorganization for Neurophysiological and Behavioral Recovery Following Stroke

Author(s): Yuan Qi*, Yujie Xu, Huailu Wang, Qiujia Wang, Meijie Li, Bo Han and Haijie Liu

Volume 24, Issue 2, 2024

Published on: 25 January, 2024

Page: [117 - 128] Pages: 12

DOI: 10.2174/0118715249277597231226064144

Price: $65

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Abstract

Stroke continues to be the main cause of motor disability worldwide. While rehabilitation has been promised to improve recovery after stroke, efficacy in clinical trials has been mixed. We need to understand the cortical recombination framework to understand how biomarkers for neurophysiological reorganized neurotechnologies alter network activity. Here, we summarize the principles of the movement network, including the current evidence of changes in the connections and function of encephalic regions, recovery from stroke and the therapeutic effects of rehabilitation. Overall, improvements or therapeutic effects in limb motor control following stroke are correlated with the effects of interhemispheric competition or compensatory models of the motor supplementary cortex. This review suggests that future research should focus on cross-regional communication and provide fundamental insights into further treatment and rehabilitation for post-stroke patients.

Keywords: Stroke, rehabilitation, brain alterations, motor disability, structural connectivity, functional connectivity.

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