Title:Incidence Rate of Post Coronary Artery Shunt Complications; Age Dependent!
Volume: 22
Issue: 4
Author(s): Basheer Abdullah Marzoog*
Affiliation:
- World-Class Research Center, Digital Biodesign and Personalized Healthcare, I.M. Sechenov First Moscow State
Medical University (Sechenov University), 119991 Moscow, Russia; Postal Address: Russia, Moscow, 8-2 Trubetskaya
street, 119991
Keywords:
Surgery, myocardial infarction, angioplasty, CABG, CVD & CVS, progressive angina.
Abstract:
Background: Numerous complications, such as postoperative arrhythmia and stroke,
have been observed following coronary artery bypass graft (CABG) surgery.
Aims: This study sought to examine the impact of aging on the incidence of post-coronary artery
shunt complications.
Objectives: Aging is a physiological process experienced by every living cell, beginning early in
development. Age plays a crucial role in determining postoperative complications, including
those related to CABG.
Materials and Methods: A retrospective analysis was conducted on 290 patients who underwent
CABG at the Mordovian Republic Hospital between 2017 and 2021. The sample was
divided into two age-based groups: the first group comprised 126 patients (mean age
range: 55.21-60.00), and the second group included 163 patients (mean age range: 66.11-80.00).
Statistical analyses employed in this study encompassed descriptive statistics, Chi-square test,
T-test, one-way ANOVA test, ROC analysis, and Pearson correlation using Statistica 12 software.
Results: Elderly patients in the second group demonstrated a higher incidence of post-CABG
arrhythmia (p < 0.012528). Moreover, the second group experienced markedly longer ICU and
total hospitalization days following CABG, with p-values of less than 0.000000 and 0.000072,
respectively. Notably, elderly individuals in the second group faced an increased risk of developing
psychosis after CABG surgery (p < 0.007379). Furthermore, psychosis was found to be
significantly associated with longer ICU hospitalization (p < 0.000140). Postoperative stroke
occurred more frequently among the elderly (second group) with a p-value of less than 0.037736.
Consequently, postoperative stroke was associated with extended ICU hospitalization
(p < 0.000747). The usage of internal thoracic arteries (ITAs) was lower among the elderly
(second group), with a p-value of less than 0.016145. Regarding correlations, a direct association
was observed between age and ICU days, total hospitalization days, and the number of complications,
with correlation coefficients (r) of 0.189046, 0.141415, and 0.138565, respectively.
Conclusion: Elderly individuals in the second group who undergo CABG face a greater risk of
developing psychosis, arrhythmia, prolonged total and ICU hospitalization, and stroke. The presence
of arrhythmia, which is commonly observed in patients aged 63 years and older, significantly
affects total hospitalization days. The number of complications is influenced by age, cardiopulmonary
bypass (CPB) time, aortic cross-clamp time, ICU hospitalization, and total hospitalization
duration.